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102,243 results
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Molecular docking and ligand specificity in fragment-based inhibitor discovery.
Chen Y, Shoichet BK. Chen Y, et al. Nat Chem Biol. 2009 May;5(5):358-64. doi: 10.1038/nchembio.155. Epub 2009 Mar 22. Nat Chem Biol. 2009. PMID: 19305397 Free PMC article.
A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing.
Shortridge MD, Walker MJ, Pavelitz T, Chen Y, Yang W, Varani G. Shortridge MD, et al. Among authors: chen y. ACS Chem Biol. 2017 Jun 16;12(6):1611-1620. doi: 10.1021/acschembio.7b00180. Epub 2017 May 2. ACS Chem Biol. 2017. PMID: 28437065 Free PMC article.
Targeted inhibition of oncogenic miR-21 maturation with designed RNA-binding proteins.
Chen Y, Yang F, Zubovic L, Pavelitz T, Yang W, Godin K, Walker M, Zheng S, Macchi P, Varani G. Chen Y, et al. Nat Chem Biol. 2016 Sep;12(9):717-23. doi: 10.1038/nchembio.2128. Epub 2016 Jul 18. Nat Chem Biol. 2016. PMID: 27428511 Free PMC article.
Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone).
Zheng S, Chen Y, Donahue CP, Wolfe MS, Varani G. Zheng S, et al. Among authors: chen y. Chem Biol. 2009 May 29;16(5):557-66. doi: 10.1016/j.chembiol.2009.03.009. Chem Biol. 2009. PMID: 19477420 Free PMC article.
Structure of stem-loop IV of Tetrahymena telomerase RNA.
Chen Y, Fender J, Legassie JD, Jarstfer MB, Bryan TM, Varani G. Chen Y, et al. EMBO J. 2006 Jul 12;25(13):3156-66. doi: 10.1038/sj.emboj.7601195. Epub 2006 Jun 15. EMBO J. 2006. PMID: 16778765 Free PMC article.
Finding the missing code of RNA recognition by PUF proteins.
Chen Y, Varani G. Chen Y, et al. Chem Biol. 2011 Jul 29;18(7):821-3. doi: 10.1016/j.chembiol.2011.07.001. Chem Biol. 2011. PMID: 21802002 Free PMC article.
A new hydrogen-bonding potential for the design of protein-RNA interactions predicts specific contacts and discriminates decoys.
Chen Y, Kortemme T, Robertson T, Baker D, Varani G. Chen Y, et al. Nucleic Acids Res. 2004 Sep 30;32(17):5147-62. doi: 10.1093/nar/gkh785. Print 2004. Nucleic Acids Res. 2004. PMID: 15459285 Free PMC article.
Cell-free selection of RNA-binding proteins using in vitro compartmentalization.
Chen Y, Mandic J, Varani G. Chen Y, et al. Nucleic Acids Res. 2008 Nov;36(19):e128. doi: 10.1093/nar/gkn559. Epub 2008 Sep 12. Nucleic Acids Res. 2008. PMID: 18790803 Free PMC article.
Protein families and RNA recognition.
Chen Y, Varani G. Chen Y, et al. FEBS J. 2005 May;272(9):2088-97. doi: 10.1111/j.1742-4658.2005.04650.x. FEBS J. 2005. PMID: 15853794 Review.
Knockdown of Foxg1 in Sox9+ supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse utricle.
Zhang Y, Zhang S, Zhang Z, Dong Y, Ma X, Qiang R, Chen Y, Gao X, Zhao C, Chen F, He S, Chai R. Zhang Y, et al. Among authors: chen y. Aging (Albany NY). 2020 Oct 24;12. doi: 10.18632/aging.104009. Online ahead of print. Aging (Albany NY). 2020. PMID: 33099273
102,243 results
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