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Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential.
Chen YB, Aon MA, Hsu YT, Soane L, Teng X, McCaffery JM, Cheng WC, Qi B, Li H, Alavian KN, Dayhoff-Brannigan M, Zou S, Pineda FJ, O'Rourke B, Ko YH, Pedersen PL, Kaczmarek LK, Jonas EA, Hardwick JM. Chen YB, et al. J Cell Biol. 2011 Oct 17;195(2):263-76. doi: 10.1083/jcb.201108059. Epub 2011 Oct 10. J Cell Biol. 2011. PMID: 21987637 Free PMC article.
Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons.
Berman SB, Chen YB, Qi B, McCaffery JM, Rucker EB 3rd, Goebbels S, Nave KA, Arnold BA, Jonas EA, Pineda FJ, Hardwick JM. Berman SB, et al. Among authors: chen yb. J Cell Biol. 2009 Mar 9;184(5):707-19. doi: 10.1083/jcb.200809060. Epub 2009 Mar 2. J Cell Biol. 2009. PMID: 19255249 Free PMC article.
Mitochondrial factors with dual roles in death and survival.
Cheng WC, Berman SB, Ivanovska I, Jonas EA, Lee SJ, Chen Y, Kaczmarek LK, Pineda F, Hardwick JM. Cheng WC, et al. Oncogene. 2006 Aug 7;25(34):4697-705. doi: 10.1038/sj.onc.1209596. Oncogene. 2006. PMID: 16892083 Review.
N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death.
Ofengeim D, Chen YB, Miyawaki T, Li H, Sacchetti S, Flannery RJ, Alavian KN, Pontarelli F, Roelofs BA, Hickman JA, Hardwick JM, Zukin RS, Jonas EA. Ofengeim D, et al. Among authors: chen yb. Nat Neurosci. 2012 Feb 26;15(4):574-80. doi: 10.1038/nn.3054. Nat Neurosci. 2012. PMID: 22366758 Free PMC article.
Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons.
Li H, Chen Y, Jones AF, Sanger RH, Collis LP, Flannery R, McNay EC, Yu T, Schwarzenbacher R, Bossy B, Bossy-Wetzel E, Bennett MV, Pypaert M, Hickman JA, Smith PJ, Hardwick JM, Jonas EA. Li H, et al. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2169-74. doi: 10.1073/pnas.0711647105. Epub 2008 Feb 4. Proc Natl Acad Sci U S A. 2008. PMID: 18250306 Free PMC article.
BAD is a pro-survival factor prior to activation of its pro-apoptotic function.
Seo SY, Chen YB, Ivanovska I, Ranger AM, Hong SJ, Dawson VL, Korsmeyer SJ, Bellows DS, Fannjiang Y, Hardwick JM. Seo SY, et al. Among authors: chen yb. J Biol Chem. 2004 Oct 1;279(40):42240-9. doi: 10.1074/jbc.M406775200. Epub 2004 Jul 1. J Biol Chem. 2004. PMID: 15231831 Free PMC article.
1,203 results