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Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A.
Walsh AH, Cheng A, Honkanen RE. Walsh AH, et al. Among authors: cheng a. FEBS Lett. 1997 Oct 27;416(3):230-4. doi: 10.1016/s0014-5793(97)01210-6. FEBS Lett. 1997. PMID: 9373158
Genomic organization of the human PP4 gene encoding a serine/threonine protein phosphatase (PP4) suggests a common ancestry with PP2A.
Huang X, Cheng A, Honkanen RE. Huang X, et al. Among authors: cheng a. Genomics. 1997 Sep 15;44(3):336-43. doi: 10.1006/geno.1997.4891. Genomics. 1997. PMID: 9325055
Dephosphorylation of human cyclin-dependent kinases by protein phosphatase type 2C alpha and beta 2 isoforms.
Cheng A, Kaldis P, Solomon MJ. Cheng A, et al. J Biol Chem. 2000 Nov 3;275(44):34744-9. doi: 10.1074/jbc.M006210200. J Biol Chem. 2000. PMID: 10934208
The effects of changing the site of activating phosphorylation in CDK2 from threonine to serine.
Kaldis P, Cheng A, Solomon MJ. Kaldis P, et al. Among authors: cheng a. J Biol Chem. 2000 Oct 20;275(42):32578-84. doi: 10.1074/jbc.M003212200. J Biol Chem. 2000. PMID: 10931829
Serine/threonine protein phosphatase type 1gamma1 is required for the completion of cytokinesis in human A549 lung carcinoma cells.
Cheng A, Dean NM, Honkanen RE. Cheng A, et al. J Biol Chem. 2000 Jan 21;275(3):1846-54. doi: 10.1074/jbc.275.3.1846. J Biol Chem. 2000. PMID: 10636884
Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases.
Cheng A, Ross KE, Kaldis P, Solomon MJ. Cheng A, et al. Genes Dev. 1999 Nov 15;13(22):2946-57. doi: 10.1101/gad.13.22.2946. Genes Dev. 1999. PMID: 10580002 Free PMC article.
Fostriecin-mediated G2-M-phase growth arrest correlates with abnormal centrosome replication, the formation of aberrant mitotic spindles, and the inhibition of serine/threonine protein phosphatase activity.
Cheng A, Balczon R, Zuo Z, Koons JS, Walsh AH, Honkanen RE. Cheng A, et al. Cancer Res. 1998 Aug 15;58(16):3611-9. Cancer Res. 1998. PMID: 9721869
Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome.
Chen EY, Cheng A, Lee A, Kuang WJ, Hillier L, Green P, Schlessinger D, Ciccodicola A, D'Urso M. Chen EY, et al. Among authors: cheng a. Genomics. 1991 Jul;10(3):792-800. doi: 10.1016/0888-7543(91)90465-q. Genomics. 1991. PMID: 1889820
Suppression of LPS-induced inflammatory responses by the hydroxyl groups of dexamethasone.
Chuang TY, Cheng AJ, Chen IT, Lan TY, Huang IH, Shiau CW, Hsu CL, Liu YW, Chang ZF, Tseng PH, Kuo JC. Chuang TY, et al. Oncotarget. 2017 Jul 25;8(30):49735-49748. doi: 10.18632/oncotarget.17683. Oncotarget. 2017. PMID: 28537905 Free PMC article.
A Combined Systemic Strategy for Overcoming Cisplatin Resistance in Head and Neck Cancer: From Target Identification to Drug Discovery.
Chen YJ, You GR, Lai MY, Lu LS, Chen CY, Ting LL, Lee HL, Kanno Y, Chiou JF, Cheng AJ. Chen YJ, et al. Among authors: cheng aj. Cancers (Basel). 2020 Nov 23;12(11):E3482. doi: 10.3390/cancers12113482. Cancers (Basel). 2020. PMID: 33238517
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