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9,426 results
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The detection of microRNA associated with Alzheimer's disease in biological fluids using next-generation sequencing technologies.
Cheng L, Quek CY, Sun X, Bellingham SA, Hill AF. Cheng L, et al. Front Genet. 2013 Aug 8;4:150. doi: 10.3389/fgene.2013.00150. eCollection 2013. Front Genet. 2013. PMID: 23964286 Free PMC article.
Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in human urine.
Cheng L, Sun X, Scicluna BJ, Coleman BM, Hill AF. Cheng L, et al. Kidney Int. 2014 Aug;86(2):433-44. doi: 10.1038/ki.2013.502. Epub 2013 Dec 18. Kidney Int. 2014. PMID: 24352158
Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood.
Cheng L, Sharples RA, Scicluna BJ, Hill AF. Cheng L, et al. J Extracell Vesicles. 2014 Mar 26;3. doi: 10.3402/jev.v3.23743. eCollection 2014. J Extracell Vesicles. 2014. PMID: 24683445 Free PMC article.
Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer's and Parkinson's Disease.
Vella LJ, Hill AF, Cheng L. Vella LJ, et al. Among authors: cheng l. Int J Mol Sci. 2016 Feb 6;17(2):173. doi: 10.3390/ijms17020173. Int J Mol Sci. 2016. PMID: 26861304 Free PMC article. Review.
Gene dysregulation is restored in the Parkinson's disease MPTP neurotoxic mice model upon treatment of the therapeutic drug Cu(II)(atsm).
Cheng L, Quek CY, Hung LW, Sharples RA, Sherratt NA, Barnham KJ, Hill AF. Cheng L, et al. Sci Rep. 2016 Mar 1;6:22398. doi: 10.1038/srep22398. Sci Rep. 2016. PMID: 26928495 Free PMC article.
Small RNA Library Construction for Exosomal RNA from Biological Samples for the Ion Torrent PGM™ and Ion S5™ System.
Cheng L, Hill AF. Cheng L, et al. Methods Mol Biol. 2017;1545:71-90. doi: 10.1007/978-1-4939-6728-5_6. Methods Mol Biol. 2017. PMID: 27943208
Defining the purity of exosomes required for diagnostic profiling of small RNA suitable for biomarker discovery.
Quek C, Bellingham SA, Jung CH, Scicluna BJ, Shambrook MC, Sharples RA, Cheng L, Hill AF. Quek C, et al. Among authors: cheng l. RNA Biol. 2017 Feb;14(2):245-258. doi: 10.1080/15476286.2016.1270005. Epub 2016 Dec 22. RNA Biol. 2017. PMID: 28005467 Free PMC article.
BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells.
Lunavat TR, Cheng L, Einarsdottir BO, Olofsson Bagge R, Veppil Muralidharan S, Sharples RA, Lässer C, Gho YS, Hill AF, Nilsson JA, Lötvall J. Lunavat TR, et al. Among authors: cheng l. Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5930-E5939. doi: 10.1073/pnas.1705206114. Epub 2017 Jul 6. Proc Natl Acad Sci U S A. 2017. PMID: 28684402 Free PMC article.
Modulating Protein Phosphatase 2A Rescues Disease Phenotype in Neurodegenerative Tauopathies.
McKenzie-Nickson S, Chan J, Perez K, Hung LW, Cheng L, Sedjahtera A, Gunawan L, Adlard PA, Hayne DJ, McInnes LE, Donnelly PS, Finkelstein DI, Hill AF, Barnham KJ. McKenzie-Nickson S, et al. Among authors: cheng l. ACS Chem Neurosci. 2018 Nov 21;9(11):2731-2740. doi: 10.1021/acschemneuro.8b00161. Epub 2018 Jul 3. ACS Chem Neurosci. 2018. PMID: 29920069
Novel miR-29b target regulation patterns are revealed in two different cell lines.
Zhao W, Cheng L, Quek C, Bellingham SA, Hill AF. Zhao W, et al. Among authors: cheng l. Sci Rep. 2019 Nov 25;9(1):17449. doi: 10.1038/s41598-019-53868-x. Sci Rep. 2019. PMID: 31767948 Free PMC article.
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