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Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice.
Pouladi MA, Stanek LM, Xie Y, Franciosi S, Southwell AL, Deng Y, Butland S, Zhang W, Cheng SH, Shihabuddin LS, Hayden MR. Pouladi MA, et al. Among authors: cheng sh. Hum Mol Genet. 2012 May 15;21(10):2219-32. doi: 10.1093/hmg/dds037. Epub 2012 Feb 9. Hum Mol Genet. 2012. PMID: 22328089
Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease.
Hadaczek P, Stanek L, Ciesielska A, Sudhakar V, Samaranch L, Pivirotto P, Bringas J, O'Riordan C, Mastis B, San Sebastian W, Forsayeth J, Cheng SH, Bankiewicz KS, Shihabuddin LS. Hadaczek P, et al. Among authors: cheng sh. Mol Ther Methods Clin Dev. 2016 Jun 29;3:16037. doi: 10.1038/mtm.2016.37. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 27408903 Free PMC article.
Magnetic resonance imaging-guided delivery of adeno-associated virus type 2 to the primate brain for the treatment of lysosomal storage disorders.
Salegio EA, Kells AP, Richardson RM, Hadaczek P, Forsayeth J, Bringas J, Sardi SP, Passini MA, Shihabuddin LS, Cheng SH, Fiandaca MS, Bankiewicz KS. Salegio EA, et al. Among authors: cheng sh. Hum Gene Ther. 2010 Sep;21(9):1093-103. doi: 10.1089/hum.2010.040. Hum Gene Ther. 2010. PMID: 20408734 Free PMC article.
CNS expression of glucocerebrosidase corrects alpha-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy.
Sardi SP, Clarke J, Kinnecom C, Tamsett TJ, Li L, Stanek LM, Passini MA, Grabowski GA, Schlossmacher MG, Sidman RL, Cheng SH, Shihabuddin LS. Sardi SP, et al. Among authors: cheng sh. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12101-6. doi: 10.1073/pnas.1108197108. Epub 2011 Jul 5. Proc Natl Acad Sci U S A. 2011. PMID: 21730160 Free PMC article.
984 results