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Gene disruption in Escherichia coli: TcR and KmR cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinant.
Cherepanov PP, Wackernagel W. Cherepanov PP, et al. Gene. 1995 May 26;158(1):9-14. doi: 10.1016/0378-1119(95)00193-a. Gene. 1995. PMID: 7789817
Characterization of a dam mutant of Serratia marcescens and nucleotide sequence of the dam region.
Ostendorf T, Cherepanov P, de Vries J, Wackernagel W. Ostendorf T, et al. Among authors: cherepanov p. J Bacteriol. 1999 Jul;181(13):3880-5. doi: 10.1128/JB.181.13.3880-3885.1999. J Bacteriol. 1999. PMID: 10383952 Free PMC article.
Expression of HIV-1 integrase in CEM cells inhibits HIV-1 replication.
van Griensven J, Zhan X, Van Maele B, Pluymers W, Michiels M, De Clercq E, Cherepanov P, Debyser Z. van Griensven J, et al. Among authors: cherepanov p. J Gene Med. 2004 Mar;6(3):268-77. doi: 10.1002/jgm.520. J Gene Med. 2004. PMID: 15026988
LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells.
Maertens G, Cherepanov P, Pluymers W, Busschots K, De Clercq E, Debyser Z, Engelborghs Y. Maertens G, et al. Among authors: cherepanov p. J Biol Chem. 2003 Aug 29;278(35):33528-39. doi: 10.1074/jbc.M303594200. Epub 2003 Jun 9. J Biol Chem. 2003. PMID: 12796494
env chimeric virus technology for evaluating human immunodeficiency virus susceptibility to entry inhibitors.
Fikkert V, Cherepanov P, Van Laethem K, Hantson A, Van Remoortel B, Pannecouque C, De Clercq E, Debyser Z, Vandamme AM, Witvrouw M. Fikkert V, et al. Among authors: cherepanov p. Antimicrob Agents Chemother. 2002 Dec;46(12):3954-62. doi: 10.1128/aac.46.12.3954-3962.2002. Antimicrob Agents Chemother. 2002. PMID: 12435701 Free PMC article.
HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells.
Cherepanov P, Maertens G, Proost P, Devreese B, Van Beeumen J, Engelborghs Y, De Clercq E, Debyser Z. Cherepanov P, et al. J Biol Chem. 2003 Jan 3;278(1):372-81. doi: 10.1074/jbc.M209278200. Epub 2002 Oct 28. J Biol Chem. 2003. PMID: 12407101
New class of HIV integrase inhibitors that block viral replication in cell culture.
Pannecouque C, Pluymers W, Van Maele B, Tetz V, Cherepanov P, De Clercq E, Witvrouw M, Debyser Z. Pannecouque C, et al. Among authors: cherepanov p. Curr Biol. 2002 Jul 23;12(14):1169-77. doi: 10.1016/s0960-9822(02)00952-1. Curr Biol. 2002. PMID: 12176326
In search of authentic inhibitors of HIV-1 integration.
Debyser Z, Cherepanov P, Van Maele B, De Clercq E, Witvrouw M. Debyser Z, et al. Among authors: cherepanov p. Antivir Chem Chemother. 2002 Jan;13(1):1-15. doi: 10.1177/095632020201300101. Antivir Chem Chemother. 2002. PMID: 12180645 Review.
Mutations in both env and gag genes are required for HIV-1 resistance to the polysulfonic dendrimer SPL2923, as corroborated by chimeric virus technology.
Hantson A, Fikkert V, Van Remoortel B, Pannecouque C, Cherepanov P, Matthews B, Holan G, De Clercq E, Vandamme AM, Debyser Z, Witvrouw M. Hantson A, et al. Among authors: cherepanov p. Antivir Chem Chemother. 2005;16(4):253-66. doi: 10.1177/095632020501600405. Antivir Chem Chemother. 2005. PMID: 16130523
HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor.
Wang H, Jurado KA, Wu X, Shun MC, Li X, Ferris AL, Smith SJ, Patel PA, Fuchs JR, Cherepanov P, Kvaratskhelia M, Hughes SH, Engelman A. Wang H, et al. Among authors: cherepanov p. Nucleic Acids Res. 2012 Dec;40(22):11518-30. doi: 10.1093/nar/gks913. Epub 2012 Oct 5. Nucleic Acids Res. 2012. PMID: 23042676 Free PMC article.
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