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Mammalian cells lacking either the cotranslational or posttranslocational oligosaccharyltransferase complex display substrate-dependent defects in asparagine linked glycosylation.
Cherepanova NA, Gilmore R. Cherepanova NA, et al. Sci Rep. 2016 Feb 11;6:20946. doi: 10.1038/srep20946. Sci Rep. 2016. PMID: 26864433 Free PMC article.
N-linked glycosylation and homeostasis of the endoplasmic reticulum.
Cherepanova N, Shrimal S, Gilmore R. Cherepanova N, et al. Curr Opin Cell Biol. 2016 Aug;41:57-65. doi: 10.1016/j.ceb.2016.03.021. Epub 2016 Apr 14. Curr Opin Cell Biol. 2016. PMID: 27085638 Free PMC article. Review.
DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon.
Shrimal S, Cherepanova NA, Gilmore R. Shrimal S, et al. Among authors: cherepanova na. J Cell Biol. 2017 Nov 6;216(11):3625-3638. doi: 10.1083/jcb.201702159. Epub 2017 Aug 31. J Cell Biol. 2017. PMID: 28860277 Free PMC article.
One flexible loop in OST lassos both substrates.
Shrimal S, Cherepanova NA, Gilmore R. Shrimal S, et al. Among authors: cherepanova na. Nat Struct Mol Biol. 2017 Dec 7;24(12):1009-1010. doi: 10.1038/nsmb.3508. Nat Struct Mol Biol. 2017. PMID: 29215637 No abstract available.
Mammalian STT3A/B oligosaccharyltransferases segregate N-glycosylation at the translocon from lipid-linked oligosaccharide hydrolysis.
Lu H, Fermaintt CS, Cherepanova NA, Gilmore R, Yan N, Lehrman MA. Lu H, et al. Among authors: cherepanova na. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9557-9562. doi: 10.1073/pnas.1806034115. Epub 2018 Sep 4. Proc Natl Acad Sci U S A. 2018. PMID: 30181269 Free PMC article.
Targeting STT3A-oligosaccharyltransferase with NGI-1 causes herpes simplex virus 1 dysfunction.
Lu H, Cherepanova NA, Gilmore R, Contessa JN, Lehrman MA. Lu H, et al. Among authors: cherepanova na. FASEB J. 2019 Jun;33(6):6801-6812. doi: 10.1096/fj.201802044RR. Epub 2019 Feb 27. FASEB J. 2019. PMID: 30811219 Free PMC article.
Mutations in MAGT1 lead to a glycosylation disorder with a variable phenotype.
Blommaert E, PĂ©anne R, Cherepanova NA, Rymen D, Staels F, Jaeken J, Race V, Keldermans L, Souche E, Corveleyn A, Sparkes R, Bhattacharya K, Devalck C, Schrijvers R, Foulquier F, Gilmore R, Matthijs G. Blommaert E, et al. Among authors: cherepanova na. Proc Natl Acad Sci U S A. 2019 May 14;116(20):9865-9870. doi: 10.1073/pnas.1817815116. Epub 2019 Apr 29. Proc Natl Acad Sci U S A. 2019. PMID: 31036665 Free PMC article.
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