Chester KA - Search Results

1

Homogeneous bispecifics by disulfide bridging.

Hull EA, Livanos M, Miranda E, Smith ME, Chester KA, Baker JR. Hull EA, et al. Among authors: chester ka. Bioconjug Chem. 2014 Aug 20;25(8):1395-401. doi: 10.1021/bc5002467. Epub 2014 Aug 1. Bioconjug Chem. 2014. PMID: 25033024 Free PMC article.

2

Tuning the Hydrolytic Stability of Next Generation Maleimide Cross-Linkers Enables Access to Albumin-Antibody Fragment Conjugates and tri-scFvs.

Forte N, Livanos M, Miranda E, Morais M, Yang X, Rajkumar VS, Chester KA, Chudasama V, Baker JR. Forte N, et al. Among authors: chester ka. Bioconjug Chem. 2018 Feb 21;29(2):486-492. doi: 10.1021/acs.bioconjchem.7b00795. Epub 2018 Jan 31. Bioconjug Chem. 2018. PMID: 29384367 Free article.

3

Homogeneous antibody fragment conjugation by disulfide bridging introduces 'spinostics'.

Schumacher FF, Sanchania VA, Tolner B, Wright ZV, Ryan CP, Smith ME, Ward JM, Caddick S, Kay CW, Aeppli G, Chester KA, Baker JR. Schumacher FF, et al. Among authors: chester ka. Sci Rep. 2013;3:1525. doi: 10.1038/srep01525. Sci Rep. 2013. PMID: 23519366 Free PMC article.

4

Acid-cleavable thiomaleamic acid linker for homogeneous antibody-drug conjugation.

Castañeda L, Maruani A, Schumacher FF, Miranda E, Chudasama V, Chester KA, Baker JR, Smith ME, Caddick S. Castañeda L, et al. Among authors: chester ka. Chem Commun (Camb). 2013 Sep 25;49(74):8187-9. doi: 10.1039/c3cc45220d. Chem Commun (Camb). 2013. PMID: 23929130 Free PMC article.

5

Next generation maleimides enable the controlled assembly of antibody-drug conjugates via native disulfide bond bridging.

Schumacher FF, Nunes JP, Maruani A, Chudasama V, Smith ME, Chester KA, Baker JR, Caddick S. Schumacher FF, et al. Among authors: chester ka. Org Biomol Chem. 2014 Oct 7;12(37):7261-9. doi: 10.1039/c4ob01550a. Org Biomol Chem. 2014. PMID: 25103319 Free PMC article.

6

Aryloxymaleimides for cysteine modification, disulfide bridging and the dual functionalization of disulfide bonds.

Marculescu C, Kossen H, Morgan RE, Mayer P, Fletcher SA, Tolner B, Chester KA, Jones LH, Baker JR. Marculescu C, et al. Among authors: chester ka. Chem Commun (Camb). 2014 Jul 11;50(54):7139-42. doi: 10.1039/c4cc02107j. Chem Commun (Camb). 2014. PMID: 24853662

7

A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy.

Maruani A, Smith ME, Miranda E, Chester KA, Chudasama V, Caddick S. Maruani A, et al. Among authors: chester ka. Nat Commun. 2015 Mar 31;6:6645. doi: 10.1038/ncomms7645. Nat Commun. 2015. PMID: 25824906 Free PMC article.

8

Generation and characterization of a diabody targeting the αvβ6 integrin.

Kogelberg H, Miranda E, Burnet J, Ellison D, Tolner B, Foster J, Picón C, Thomas GJ, Meyer T, Marshall JF, Mather SJ, Chester K. Kogelberg H, et al. PLoS One. 2013 Sep 4;8(9):e73260. doi: 10.1371/journal.pone.0073260. eCollection 2013. PLoS One. 2013. PMID: 24023846 Free PMC article.

9

Development of the designed ankyrin repeat protein (DARPin) G3 for HER2 molecular imaging.

Goldstein R, Sosabowski J, Livanos M, Leyton J, Vigor K, Bhavsar G, Nagy-Davidescu G, Rashid M, Miranda E, Yeung J, Tolner B, Plückthun A, Mather S, Meyer T, Chester K. Goldstein R, et al. Eur J Nucl Med Mol Imaging. 2015 Feb;42(2):288-301. doi: 10.1007/s00259-014-2940-2. Epub 2014 Nov 13. Eur J Nucl Med Mol Imaging. 2015. PMID: 25391547 Free PMC article.

10

Site-specific polysialylation of an antitumor single-chain Fv fragment.

Constantinou A, Epenetos AA, Hreczuk-Hirst D, Jain S, Wright M, Chester KA, Deonarain MP. Constantinou A, et al. Among authors: chester ka. Bioconjug Chem. 2009 May 20;20(5):924-31. doi: 10.1021/bc8005122. Bioconjug Chem. 2009. PMID: 19402707

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