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Transduction mechanisms of porcine chondrocyte inorganic pyrophosphate elaboration.
Ryan LM, Kurup IV, Cheung HS. Ryan LM, et al. Arthritis Rheum. 1999 Mar;42(3):555-60. doi: 10.1002/1529-0131(199904)42:3<555::AID-ANR21>3.0.CO;2-Z. Arthritis Rheum. 1999. PMID: 10088779
p53 down-regulates human matrix metalloproteinase-1 (Collagenase-1) gene expression.
Sun Y, Sun Y, Wenger L, Rutter JL, Brinckerhoff CE, Cheung HS. Sun Y, et al. J Biol Chem. 1999 Apr 23;274(17):11535-40. doi: 10.1074/jbc.274.17.11535. J Biol Chem. 1999. PMID: 10206959
Basic calcium phosphate crystal induction of collagenase 1 and stromelysin expression is dependent on a p42/44 mitogen-activated protein kinase signal transduction pathway.
Brogley MA, Cruz M, Cheung HS. Brogley MA, et al. J Cell Physiol. 1999 Aug;180(2):215-24. doi: 10.1002/(SICI)1097-4652(199908)180:2<215::AID-JCP9>3.0.CO;2-J. J Cell Physiol. 1999. PMID: 10395291
Human metalloproteinase-1 (collagenase-1) is a tumor suppressor protein p53 target gene.
Sun Y, Sun Y, Wenger L, Rutter JL, Brinckerhoff CE, Cheung HS. Sun Y, et al. Ann N Y Acad Sci. 1999 Jun 30;878:638-41. doi: 10.1111/j.1749-6632.1999.tb07749.x. Ann N Y Acad Sci. 1999. PMID: 10415795 No abstract available.
Wild type and mutant p53 differentially regulate the gene expression of human collagenase-3 (hMMP-13).
Sun Y, Cheung JM, Martel-Pelletier J, Pelletier JP, Wenger L, Altman RD, Howell DS, Cheung HS. Sun Y, et al. J Biol Chem. 2000 Apr 14;275(15):11327-32. doi: 10.1074/jbc.275.15.11327. J Biol Chem. 2000. PMID: 10753945
., and Cheung, H. S. (1999) J. Biol. Chem. 274, 11535-11540). Here, we report that cotransfection of fibroblast-like synoviocytes with p53 expression and hMMP13CAT reporter plasmids revealed that (i) hMMP13, another member of the human MMP family, was down-regulated by wil …
., and Cheung, H. S. (1999) J. Biol. Chem. 274, 11535-11540). Here, we report that cotransfection of fibroblast-like synoviocytes wit …
Basic calcium phosphate crystals up-regulate metalloproteinases but down-regulate tissue inhibitor of metalloproteinase-1 and -2 in human fibroblasts.
Bai G, Howell DS, Howard GA, Roos BA, Cheung HS. Bai G, et al. Osteoarthritis Cartilage. 2001 Jul;9(5):416-22. doi: 10.1053/joca.2000.0407. Osteoarthritis Cartilage. 2001. PMID: 11467889
Basic calcium phosphate crystals induce matrix metalloproteinase-1 through the Ras/mitogen-activated protein kinase/c-Fos/AP-1/metalloproteinase 1 pathway. Involvement of transcription factor binding sites AP-1 and PEA-3.
Sun Y, Wenger L, Brinckerhoff CE, Misra RR, Cheung HS. Sun Y, et al. J Biol Chem. 2002 Jan 11;277(2):1544-52. doi: 10.1074/jbc.M100567200. Epub 2001 Oct 26. J Biol Chem. 2002. PMID: 11682465
Molecular mechanism of the induction of metalloproteinases 1 and 3 in human fibroblasts by basic calcium phosphate crystals. Role of calcium-dependent protein kinase C alpha.
Reuben PM, Brogley MA, Sun Y, Cheung HS. Reuben PM, et al. J Biol Chem. 2002 Apr 26;277(17):15190-8. doi: 10.1074/jbc.M200278200. Epub 2002 Feb 8. J Biol Chem. 2002. PMID: 11836255
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