Chevalier KM - Search Results

1

Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity.

Douglass JD, Zhou YX, Wu A, Zadroga JA, Gajda AM, Lackey AI, Lang W, Chevalier KM, Sutton SW, Zhang SP, Flores CM, Connelly MA, Storch J. Douglass JD, et al. Among authors: chevalier km. J Lipid Res. 2015 Jun;56(6):1153-71. doi: 10.1194/jlr.M058586. Epub 2015 Apr 4. J Lipid Res. 2015. PMID: 25842377 Free PMC article.

2

Erratum: Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity.

Douglass JD, Zhou YX, Wu A, Zadroga JA, Gajda AM, Lackey AI, Lang W, Chevalier KM, Sutton SW, Zhang SP, Flores CM, Connelly MA, Storch J. Douglass JD, et al. Among authors: chevalier km. J Lipid Res. 2019 Mar;60(3):717. doi: 10.1194/jlr.M058586ERR. J Lipid Res. 2019. PMID: 30824679 Free PMC article. No abstract available.

3

The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL).

Zhu B, Connolly PJ, Zhang SP, Chevalier KM, Milligan CM, Flores CM, Macielag MJ. Zhu B, et al. Among authors: chevalier km. Bioorg Med Chem Lett. 2020 Jun 15;30(12):127198. doi: 10.1016/j.bmcl.2020.127198. Epub 2020 Apr 18. Bioorg Med Chem Lett. 2020. PMID: 32334914

4

Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor.

Wyatt RM, Fraser I, Welty N, Lord B, Wennerholm M, Sutton S, Ameriks MK, Dugovic C, Yun S, White A, Nguyen L, Koudriakova T, Tian G, Suarez J, Szewczuk L, Bonnette W, Ahn K, Ghosh B, Flores CM, Connolly PJ, Zhu B, Macielag MJ, Brandt MR, Chevalier K, Zhang SP, Lovenberg T, Bonaventure P. Wyatt RM, et al. J Pharmacol Exp Ther. 2020 Mar;372(3):339-353. doi: 10.1124/jpet.119.262139. Epub 2019 Dec 9. J Pharmacol Exp Ther. 2020. PMID: 31818916

5

The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors.

Zhu B, Connolly PJ, Zhang YM, McDonnell ME, Bian H, Lin SC, Liu L, Zhang SP, Chevalier KM, Brandt MR, Milligan CM, Flores CM, Macielag MJ. Zhu B, et al. Among authors: chevalier km. Bioorg Med Chem Lett. 2020 Jul 15;30(14):127243. doi: 10.1016/j.bmcl.2020.127243. Epub 2020 May 7. Bioorg Med Chem Lett. 2020. PMID: 32527545

6

Ex vivo delta opioid receptor autoradiography: CNS receptor occupancy of two novel compounds over their antihyperalgesic dose range.

Codd EE, Ma J, Zhang SP, Stone DJ Jr, Colburn RW, Brandt MR, Chevalier KM, Zhu Y, Peng S, Cai C, Acton PD, Flores CM. Codd EE, et al. Among authors: chevalier km. Pharmacol Biochem Behav. 2010 Aug;96(2):130-5. doi: 10.1016/j.pbb.2010.04.020. Epub 2010 May 12. Pharmacol Biochem Behav. 2010. PMID: 20438745

7

Diabetogenic effect of a series of tricyclic delta opioid agonists structurally related to cyproheptadine.

Codd EE, Baker J, Brandt MR, Bryant S, Cai C, Carson JR, Chevalier KM, Colburn RW, Coogan TP, Dax SL, Decorte B, Kemmerer M, Legrand EK, Lenhard JM, Leone AM, Lin L, Mabus JR, McDonnell ME, McMillian MK, McNally JJ, Stone DJ Jr, Wang CY, Zhang SP, Flores CM. Codd EE, et al. Among authors: chevalier km. Toxicol Sci. 2010 Oct;117(2):493-504. doi: 10.1093/toxsci/kfq200. Epub 2010 Jul 8. Toxicol Sci. 2010. PMID: 20616206

8

A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors.

Moores SL, Chiu ML, Bushey BS, Chevalier K, Luistro L, Dorn K, Brezski RJ, Haytko P, Kelly T, Wu SJ, Martin PL, Neijssen J, Parren PW, Schuurman J, Attar RM, Laquerre S, Lorenzi MV, Anderson GM. Moores SL, et al. Cancer Res. 2016 Jul 1;76(13):3942-53. doi: 10.1158/0008-5472.CAN-15-2833. Epub 2016 May 23. Cancer Res. 2016. PMID: 27216193

9

Modulation of gastrointestinal function by MuDelta, a mixed µ opioid receptor agonist/ µ opioid receptor antagonist.

Wade PR, Palmer JM, McKenney S, Kenigs V, Chevalier K, Moore BA, Mabus JR, Saunders PR, Wallace NH, Schneider CR, Kimball ES, Breslin HJ, He W, Hornby PJ. Wade PR, et al. Br J Pharmacol. 2012 Nov;167(5):1111-25. doi: 10.1111/j.1476-5381.2012.02068.x. Br J Pharmacol. 2012. PMID: 22671931 Free PMC article.

10

Triazinediones as prokineticin 1 receptor antagonists. Part 1: SAR, synthesis and biological evaluation.

Ralbovsky JL, Lisko JG, Palmer JM, Mabus J, Chevalier KM, Schulz MJ, Dyatkin AB, Miskowski TA, Coats SJ, Hornby P, He W. Ralbovsky JL, et al. Among authors: chevalier km. Bioorg Med Chem Lett. 2009 May 15;19(10):2661-3. doi: 10.1016/j.bmcl.2009.03.157. Epub 2009 Apr 5. Bioorg Med Chem Lett. 2009. PMID: 19375913

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