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122 results
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Listening to silence and understanding nonsense: exonic mutations that affect splicing.
Cartegni L, Chew SL, Krainer AR. Cartegni L, et al. Among authors: chew sl. Nat Rev Genet. 2002 Apr;3(4):285-98. doi: 10.1038/nrg775. Nat Rev Genet. 2002. PMID: 11967553 Review.
An increased specificity score matrix for the prediction of SF2/ASF-specific exonic splicing enhancers.
Smith PJ, Zhang C, Wang J, Chew SL, Zhang MQ, Krainer AR. Smith PJ, et al. Among authors: chew sl. Hum Mol Genet. 2006 Aug 15;15(16):2490-508. doi: 10.1093/hmg/ddl171. Epub 2006 Jul 6. Hum Mol Genet. 2006. PMID: 16825284
Putting some spine into alternative splicing.
Khoo B, Akker SA, Chew SL. Khoo B, et al. Among authors: chew sl. Trends Biotechnol. 2003 Aug;21(8):328-30. doi: 10.1016/S0167-7799(03)00168-9. Trends Biotechnol. 2003. PMID: 12902166
An exonic splicing enhancer in human IGF-I pre-mRNA mediates recognition of alternative exon 5 by the serine-arginine protein splicing factor-2/alternative splicing factor.
Smith PJ, Spurrell EL, Coakley J, Hinds CJ, Ross RJ, Krainer AR, Chew SL. Smith PJ, et al. Among authors: chew sl. Endocrinology. 2002 Jan;143(1):146-54. doi: 10.1210/endo.143.1.8598. Endocrinology. 2002. PMID: 11751603
Evidence for the function of an exonic splicing enhancer after the first catalytic step of pre-mRNA splicing.
Chew SL, Liu HX, Mayeda A, Krainer AR. Chew SL, et al. Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10655-60. doi: 10.1073/pnas.96.19.10655. Proc Natl Acad Sci U S A. 1999. PMID: 10485881 Free PMC article.
Exonic splicing enhancer motif recognized by human SC35 under splicing conditions.
Liu HX, Chew SL, Cartegni L, Zhang MQ, Krainer AR. Liu HX, et al. Among authors: chew sl. Mol Cell Biol. 2000 Feb;20(3):1063-71. doi: 10.1128/mcb.20.3.1063-1071.2000. Mol Cell Biol. 2000. PMID: 10629063 Free PMC article.
An exonic splicing silencer in the testes-specific DNA ligase III beta exon.
Chew SL, Baginsky L, Eperon IC. Chew SL, et al. Nucleic Acids Res. 2000 Jan 15;28(2):402-10. doi: 10.1093/nar/28.2.402. Nucleic Acids Res. 2000. PMID: 10606636 Free PMC article.
Pre-spliceosomal binding of U1 small nuclear ribonucleoprotein (RNP) and heterogenous nuclear RNP E1 is associated with suppression of a growth hormone receptor pseudoexon.
Akker SA, Misra S, Aslam S, Morgan EL, Smith PJ, Khoo B, Chew SL. Akker SA, et al. Among authors: chew sl. Mol Endocrinol. 2007 Oct;21(10):2529-40. doi: 10.1210/me.2007-0038. Epub 2007 Jul 10. Mol Endocrinol. 2007. PMID: 17622584
A short isoform of the human growth hormone receptor functions as a dominant negative inhibitor of the full-length receptor and generates large amounts of binding protein.
Ross RJ, Esposito N, Shen XY, Von Laue S, Chew SL, Dobson PR, Postel-Vinay MC, Finidori J. Ross RJ, et al. Among authors: chew sl. Mol Endocrinol. 1997 Mar;11(3):265-73. doi: 10.1210/mend.11.3.9901. Mol Endocrinol. 1997. PMID: 9058373
An alternatively spliced human insulin-like growth factor-I transcript with hepatic tissue expression that diverts away from the mitogenic IBE1 peptide.
Chew SL, Lavender P, Clark AJ, Ross RJ. Chew SL, et al. Endocrinology. 1995 May;136(5):1939-44. doi: 10.1210/endo.136.5.7720641. Endocrinology. 1995. PMID: 7720641
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