Chhabra S - Search Results

1

Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases.

Chhabra S, Chang SC, Nguyen HM, Huq R, Tanner MR, Londono LM, Estrada R, Dhawan V, Chauhan S, Upadhyay SK, Gindin M, Hotez PJ, Valenzuela JG, Mohanty B, Swarbrick JD, Wulff H, Iadonato SP, Gutman GA, Beeton C, Pennington MW, Norton RS, Chandy KG. Chhabra S, et al. FASEB J. 2014 Sep;28(9):3952-64. doi: 10.1096/fj.14-251967. Epub 2014 Jun 2. FASEB J. 2014. PMID: 24891519 Free PMC article.

2

Development of highly selective Kv1.3-blocking peptides based on the sea anemone peptide ShK.

Pennington MW, Chang SC, Chauhan S, Huq R, Tajhya RB, Chhabra S, Norton RS, Beeton C. Pennington MW, et al. Among authors: chhabra s. Mar Drugs. 2015 Jan 16;13(1):529-42. doi: 10.3390/md13010529. Mar Drugs. 2015. PMID: 25603346 Free PMC article.

3

N-Terminally extended analogues of the K⁺ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3.

Chang SC, Huq R, Chhabra S, Beeton C, Pennington MW, Smith BJ, Norton RS. Chang SC, et al. Among authors: chhabra s. FEBS J. 2015 Jun;282(12):2247-59. doi: 10.1111/febs.13294. Epub 2015 Apr 23. FEBS J. 2015. PMID: 25864722 Free PMC article.

4

Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats.

Bergmann R, Kubeil M, Zarschler K, Chhabra S, Tajhya RB, Beeton C, Pennington MW, Bachmann M, Norton RS, Stephan H. Bergmann R, et al. Among authors: chhabra s. Sci Rep. 2017 Jun 16;7(1):3756. doi: 10.1038/s41598-017-03998-x. Sci Rep. 2017. PMID: 28623364 Free PMC article.

5

A potent and Kv1.3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases.

Rashid MH, Huq R, Tanner MR, Chhabra S, Khoo KK, Estrada R, Dhawan V, Chauhan S, Pennington MW, Beeton C, Kuyucak S, Norton RS. Rashid MH, et al. Among authors: chhabra s. Sci Rep. 2014 Mar 28;4:4509. doi: 10.1038/srep04509. Sci Rep. 2014. PMID: 24676092 Free PMC article.

6

Reinvestigation of the biological activity of d-allo-ShK protein.

Dang B, Chhabra S, Pennington MW, Norton RS, Kent SBH. Dang B, et al. Among authors: chhabra s. J Biol Chem. 2017 Jul 28;292(30):12599-12605. doi: 10.1074/jbc.M117.793943. Epub 2017 Jun 8. J Biol Chem. 2017. PMID: 28596383 Free PMC article.

7

A potent and selective peptide blocker of the Kv1.3 channel: prediction from free-energy simulations and experimental confirmation.

Rashid MH, Heinzelmann G, Huq R, Tajhya RB, Chang SC, Chhabra S, Pennington MW, Beeton C, Norton RS, Kuyucak S. Rashid MH, et al. Among authors: chhabra s. PLoS One. 2013 Nov 7;8(11):e78712. doi: 10.1371/journal.pone.0078712. eCollection 2013. PLoS One. 2013. PMID: 24244345 Free PMC article.

8

Conformational flexibility in the binding surface of the potassium channel blocker ShK.

Sher I, Chang SC, Li Y, Chhabra S, Palmer AG 3rd, Norton RS, Chill JH. Sher I, et al. Among authors: chhabra s. Chembiochem. 2014 Nov 3;15(16):2402-10. doi: 10.1002/cbic.201402295. Epub 2014 Sep 18. Chembiochem. 2014. PMID: 25236806 Free PMC article.

9

Stereoselective synthesis and structural elucidation of dicarba peptides.

Gleeson EC, Wang ZJ, Robinson SD, Chhabra S, MacRaild CA, Jackson WR, Norton RS, Robinson AJ. Gleeson EC, et al. Among authors: chhabra s. Chem Commun (Camb). 2016 Mar 25;52(24):4446-9. doi: 10.1039/c5cc10540d. Chem Commun (Camb). 2016. PMID: 26892179

10

Installation of a Rigid EDTA-Like Motif into a Protein α-Helix for Paramagnetic NMR Spectroscopy with Cobalt(II) Ions.

Swarbrick JD, Ung P, Dennis ML, Lee MD, Chhabra S, Graham B. Swarbrick JD, et al. Among authors: chhabra s. Chemistry. 2016 Jan 22;22(4):1228-32. doi: 10.1002/chem.201503139. Epub 2015 Dec 17. Chemistry. 2016. PMID: 26634335

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