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Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia.
Draper-Joyce CJ, Bhola R, Wang J, Bhattarai A, Nguyen ATN, Cowie-Kent I, O'Sullivan K, Chia LY, Venugopal H, Valant C, Thal DM, Wootten D, Panel N, Carlsson J, Christie MJ, White PJ, Scammells P, May LT, Sexton PM, Danev R, Miao Y, Glukhova A, Imlach WL, Christopoulos A. Draper-Joyce CJ, et al. Among authors: chia ly. Nature. 2021 Sep;597(7877):571-576. doi: 10.1038/s41586-021-03897-2. Epub 2021 Sep 8. Nature. 2021. PMID: 34497422 Free PMC article.
The metabolic effects of mirabegron are mediated primarily by β3 -adrenoceptors.
Dehvari N, Sato M, Bokhari MH, Kalinovich A, Ham S, Gao J, Nguyen HTM, Whiting L, Mukaida S, Merlin J, Chia LY, Wootten D, Summers RJ, Evans BA, Bengtsson T, Hutchinson DS. Dehvari N, et al. Among authors: chia ly. Pharmacol Res Perspect. 2020 Oct;8(5):e00643. doi: 10.1002/prp2.643. Pharmacol Res Perspect. 2020. PMID: 32813332 Free PMC article.
α1A-Adrenoceptors activate mTOR signalling and glucose uptake in cardiomyocytes.
Sato M, Evans BA, Sandström AL, Chia LY, Mukaida S, Thai BS, Nguyen A, Lim L, Tan CYR, Baltos JA, White PJ, May LT, Hutchinson DS, Summers RJ, Bengtsson T. Sato M, et al. Among authors: chia ly. Biochem Pharmacol. 2018 Feb;148:27-40. doi: 10.1016/j.bcp.2017.11.016. Epub 2017 Nov 24. Biochem Pharmacol. 2018. PMID: 29175420 Free article.
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