Chiang EY - Search Results

1

Targeted depletion of lymphotoxin-alpha-expressing TH1 and TH17 cells inhibits autoimmune disease.

Chiang EY, Kolumam GA, Yu X, Francesco M, Ivelja S, Peng I, Gribling P, Shu J, Lee WP, Refino CJ, Balazs M, Paler-Martinez A, Nguyen A, Young J, Barck KH, Carano RA, Ferrando R, Diehl L, Chatterjea D, Grogan JL. Chiang EY, et al. Nat Med. 2009 Jul;15(7):766-73. doi: 10.1038/nm.1984. Epub 2009 Jun 28. Nat Med. 2009. PMID: 19561618

2

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Yu X, Harden K, Gonzalez LC, Francesco M, Chiang E, Irving B, Tom I, Ivelja S, Refino CJ, Clark H, Eaton D, Grogan JL. Yu X, et al. Nat Immunol. 2009 Jan;10(1):48-57. doi: 10.1038/ni.1674. Epub 2008 Nov 16. Nat Immunol. 2009. PMID: 19011627

3

Lymphotoxin-alphabeta heterotrimers are cleaved by metalloproteinases and contribute to synovitis in rheumatoid arthritis.

Young J, Yu X, Wolslegel K, Nguyen A, Kung C, Chiang E, Kolumam G, Wei N, Wong WL, DeForge L, Townsend MJ, Grogan JL. Young J, et al. Cytokine. 2010 Jul;51(1):78-86. doi: 10.1016/j.cyto.2010.03.003. Epub 2010 Mar 31. Cytokine. 2010. PMID: 20356761

4

Immune complex-mediated cell activation from systemic lupus erythematosus and rheumatoid arthritis patients elaborate different requirements for IRAK1/4 kinase activity across human cell types.

Chiang EY, Yu X, Grogan JL. Chiang EY, et al. J Immunol. 2011 Jan 15;186(2):1279-88. doi: 10.4049/jimmunol.1002821. Epub 2010 Dec 15. J Immunol. 2011. PMID: 21160042

5

In vivo depletion of lymphotoxin-alpha expressing lymphocytes inhibits xenogeneic graft-versus-host-disease.

Chiang EY, Kolumam G, McCutcheon KM, Young J, Lin Z, Balazs M, Grogan JL. Chiang EY, et al. PLoS One. 2012;7(3):e33106. doi: 10.1371/journal.pone.0033106. Epub 2012 Mar 12. PLoS One. 2012. PMID: 22427961 Free PMC article.

6

Controlling herpetic stromal keratitis by modulating lymphotoxin-alpha-mediated inflammatory pathways.

Veiga-Parga T, Giménez F, Mulik S, Chiang EY, Grogan JL, Rouse BT. Veiga-Parga T, et al. Among authors: chiang ey. Microbes Infect. 2013 Sep-Oct;15(10-11):677-87. doi: 10.1016/j.micinf.2013.07.001. Epub 2013 Jul 10. Microbes Infect. 2013. PMID: 23850656 Free PMC article.

7

Dimerization of LTβR by LTα1β2 is necessary and sufficient for signal transduction.

Sudhamsu J, Yin J, Chiang EY, Starovasnik MA, Grogan JL, Hymowitz SG. Sudhamsu J, et al. Among authors: chiang ey. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19896-901. doi: 10.1073/pnas.1310838110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248355 Free PMC article.

8

EBI2 is a negative regulator of type I interferons in plasmacytoid and myeloid dendritic cells.

Chiang EY, Johnston RJ, Grogan JL. Chiang EY, et al. PLoS One. 2013 Dec 26;8(12):e83457. doi: 10.1371/journal.pone.0083457. eCollection 2013. PLoS One. 2013. PMID: 24386204 Free PMC article.

9

Evaluating the Use of Antibody Variable Region (Fv) Charge as a Risk Assessment Tool for Predicting Typical Cynomolgus Monkey Pharmacokinetics.

Bumbaca Yadav D, Sharma VK, Boswell CA, Hotzel I, Tesar D, Shang Y, Ying Y, Fischer SK, Grogan JL, Chiang EY, Urban K, Ulufatu S, Khawli LA, Prabhu S, Joseph S, Kelley RF. Bumbaca Yadav D, et al. Among authors: chiang ey. J Biol Chem. 2015 Dec 11;290(50):29732-41. doi: 10.1074/jbc.M115.692434. Epub 2015 Oct 21. J Biol Chem. 2015. PMID: 26491012 Free PMC article.

10

TIGIT: A Key Inhibitor of the Cancer Immunity Cycle.

Manieri NA, Chiang EY, Grogan JL. Manieri NA, et al. Among authors: chiang ey. Trends Immunol. 2017 Jan;38(1):20-28. doi: 10.1016/j.it.2016.10.002. Epub 2016 Oct 25. Trends Immunol. 2017. PMID: 27793572 Review.

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