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Identification of the Nicotinamide Salvage Pathway as a New Toxification Route for Antimetabolites.
Buonvicino D, Mazzola F, Zamporlini F, Resta F, Ranieri G, Camaioni E, Muzzi M, Zecchi R, Pieraccini G, Dölle C, Calamante M, Bartolucci G, Ziegler M, Stecca B, Raffaelli N, Chiarugi A. Buonvicino D, et al. Among authors: chiarugi a. Cell Chem Biol. 2018 Apr 19;25(4):471-482.e7. doi: 10.1016/j.chembiol.2018.01.012. Epub 2018 Feb 22. Cell Chem Biol. 2018. PMID: 29478906 Free article.
Poly(ADP-ribose) catabolism triggers AMP-dependent mitochondrial energy failure.
Formentini L, Macchiarulo A, Cipriani G, Camaioni E, Rapizzi E, Pellicciari R, Moroni F, Chiarugi A. Formentini L, et al. Among authors: chiarugi a. J Biol Chem. 2009 Jun 26;284(26):17668-76. doi: 10.1074/jbc.M109.002931. Epub 2009 May 1. J Biol Chem. 2009. PMID: 19411252 Free PMC article.
Long-lasting neuroprotection and neurological improvement in stroke models with new, potent and brain permeable inhibitors of poly(ADP-ribose) polymerase.
Moroni F, Cozzi A, Chiarugi A, Formentini L, Camaioni E, Pellegrini-Giampietro DE, Chen Y, Liang S, Zaleska MM, Gonzales C, Wood A, Pellicciari R. Moroni F, et al. Among authors: chiarugi a. Br J Pharmacol. 2012 Mar;165(5):1487-500. doi: 10.1111/j.1476-5381.2011.01666.x. Br J Pharmacol. 2012. PMID: 21913897 Free PMC article.
Ischemic neuroprotection by TRPV1 receptor-induced hypothermia.
Muzzi M, Felici R, Cavone L, Gerace E, Minassi A, Appendino G, Moroni F, Chiarugi A. Muzzi M, et al. Among authors: chiarugi a. J Cereb Blood Flow Metab. 2012 Jun;32(6):978-82. doi: 10.1038/jcbfm.2012.36. Epub 2012 Mar 21. J Cereb Blood Flow Metab. 2012. PMID: 22434066 Free PMC article.
193 results