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BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance.
Tasdemir N, Banito A, Roe JS, Alonso-Curbelo D, Camiolo M, Tschaharganeh DF, Huang CH, Aksoy O, Bolden JE, Chen CC, Fennell M, Thapar V, Chicas A, Vakoc CR, Lowe SW. Tasdemir N, et al. Among authors: chicas a. Cancer Discov. 2016 Jun;6(6):612-29. doi: 10.1158/2159-8290.CD-16-0217. Epub 2016 Apr 20. Cancer Discov. 2016. PMID: 27099234 Free PMC article.
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway.
Freed-Pastor WA, Mizuno H, Zhao X, Langerød A, Moon SH, Rodriguez-Barrueco R, Barsotti A, Chicas A, Li W, Polotskaia A, Bissell MJ, Osborne TF, Tian B, Lowe SW, Silva JM, Børresen-Dale AL, Levine AJ, Bargonetti J, Prives C. Freed-Pastor WA, et al. Among authors: chicas a. Cell. 2012 Jan 20;148(1-2):244-58. doi: 10.1016/j.cell.2011.12.017. Cell. 2012. PMID: 22265415 Free PMC article.
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, Magoon D, Qi J, Blatt K, Wunderlich M, Taylor MJ, Johns C, Chicas A, Mulloy JC, Kogan SC, Brown P, Valent P, Bradner JE, Lowe SW, Vakoc CR. Zuber J, et al. Among authors: chicas a. Nature. 2011 Aug 3;478(7370):524-8. doi: 10.1038/nature10334. Nature. 2011. PMID: 21814200 Free PMC article.
Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation.
Chandra T, Kirschner K, Thuret JY, Pope BD, Ryba T, Newman S, Ahmed K, Samarajiwa SA, Salama R, Carroll T, Stark R, Janky R, Narita M, Xue L, Chicas A, Nũnez S, Janknecht R, Hayashi-Takanaka Y, Wilson MD, Marshall A, Odom DT, Babu MM, Bazett-Jones DP, Tavaré S, Edwards PA, Lowe SW, Kimura H, Gilbert DM, Narita M. Chandra T, et al. Among authors: chicas a. Mol Cell. 2012 Jul 27;47(2):203-14. doi: 10.1016/j.molcel.2012.06.010. Epub 2012 Jul 12. Mol Cell. 2012. PMID: 22795131 Free PMC article.
22 results