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Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis.
Lefebvre P, Chinetti G, Fruchart JC, Staels B. Lefebvre P, et al. Among authors: chinetti g. J Clin Invest. 2006 Mar;116(3):571-80. doi: 10.1172/JCI27989. J Clin Invest. 2006. PMID: 16511589 Free PMC article. Review.
Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators.
Staels B, Koenig W, Habib A, Merval R, Lebret M, Torra IP, Delerive P, Fadel A, Chinetti G, Fruchart JC, Najib J, Maclouf J, Tedgui A. Staels B, et al. Among authors: chinetti g. Nature. 1998 Jun 25;393(6687):790-3. doi: 10.1038/31701. Nature. 1998. PMID: 9655393
Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages.
Chinetti G, Griglio S, Antonucci M, Torra IP, Delerive P, Majd Z, Fruchart JC, Chapman J, Najib J, Staels B. Chinetti G, et al. J Biol Chem. 1998 Oct 2;273(40):25573-80. doi: 10.1074/jbc.273.40.25573. J Biol Chem. 1998. PMID: 9748221
Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway.
Delerive P, Martin-Nizard F, Chinetti G, Trottein F, Fruchart JC, Najib J, Duriez P, Staels B. Delerive P, et al. Among authors: chinetti g. Circ Res. 1999 Sep 3;85(5):394-402. doi: 10.1161/01.res.85.5.394. Circ Res. 1999. PMID: 10473669
A truncated human peroxisome proliferator-activated receptor alpha splice variant with dominant negative activity.
Gervois P, Torra IP, Chinetti G, Grötzinger T, Dubois G, Fruchart JC, Fruchart-Najib J, Leitersdorf E, Staels B. Gervois P, et al. Among authors: chinetti g. Mol Endocrinol. 1999 Sep;13(9):1535-49. doi: 10.1210/mend.13.9.0341. Mol Endocrinol. 1999. PMID: 10478844
Cell culture conditions determine apolipoprotein CIII secretion and regulation by fibrates in human hepatoma HepG2 cells.
Clavey V, Copin C, Mariotte MC, Baugé E, Chinetti G, Fruchart J, Fruchart JC, Dallongeville J, Staels B. Clavey V, et al. Among authors: chinetti g. Cell Physiol Biochem. 1999;9(3):139-49. doi: 10.1159/000016311. Cell Physiol Biochem. 1999. PMID: 10494028
CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors.
Chinetti G, Gbaguidi FG, Griglio S, Mallat Z, Antonucci M, Poulain P, Chapman J, Fruchart JC, Tedgui A, Najib-Fruchart J, Staels B. Chinetti G, et al. Circulation. 2000 May 23;101(20):2411-7. doi: 10.1161/01.cir.101.20.2411. Circulation. 2000. PMID: 10821819
Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation.
Chinetti G, Fruchart JC, Staels B. Chinetti G, et al. Inflamm Res. 2000 Oct;49(10):497-505. doi: 10.1007/s000110050622. Inflamm Res. 2000. PMID: 11089900 Review.
Peroxisome proliferator-activated receptor gamma activators inhibit interleukin-12 production in murine dendritic cells.
Faveeuw C, Fougeray S, Angeli V, Fontaine J, Chinetti G, Gosset P, Delerive P, Maliszewski C, Capron M, Staels B, Moser M, Trottein F. Faveeuw C, et al. Among authors: chinetti g. FEBS Lett. 2000 Dec 15;486(3):261-6. doi: 10.1016/s0014-5793(00)02319-x. FEBS Lett. 2000. PMID: 11119715
PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway.
Chinetti G, Lestavel S, Bocher V, Remaley AT, Neve B, Torra IP, Teissier E, Minnich A, Jaye M, Duverger N, Brewer HB, Fruchart JC, Clavey V, Staels B. Chinetti G, et al. Nat Med. 2001 Jan;7(1):53-8. doi: 10.1038/83348. Nat Med. 2001. PMID: 11135616
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