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Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARγ and LXRα pathways.
Chinetti-Gbaguidi G, Baron M, Bouhlel MA, Vanhoutte J, Copin C, Sebti Y, Derudas B, Mayi T, Bories G, Tailleux A, Haulon S, Zawadzki C, Jude B, Staels B. Chinetti-Gbaguidi G, et al. Circ Res. 2011 Apr 15;108(8):985-95. doi: 10.1161/CIRCRESAHA.110.233775. Epub 2011 Feb 24. Circ Res. 2011. PMID: 21350215 Free PMC article.
Peroxisome proliferator-activated receptor-γ activation induces 11β-hydroxysteroid dehydrogenase type 1 activity in human alternative macrophages.
Chinetti-Gbaguidi G, Bouhlel MA, Copin C, Duhem C, Derudas B, Neve B, Noel B, Eeckhoute J, Lefebvre P, Seckl JR, Staels B. Chinetti-Gbaguidi G, et al. Arterioscler Thromb Vasc Biol. 2012 Mar;32(3):677-85. doi: 10.1161/ATVBAHA.111.241364. Epub 2011 Dec 29. Arterioscler Thromb Vasc Biol. 2012. PMID: 22207732 Free PMC article.
Liver X receptor activation stimulates iron export in human alternative macrophages.
Bories G, Colin S, Vanhoutte J, Derudas B, Copin C, Fanchon M, Daoudi M, Belloy L, Haulon S, Zawadzki C, Jude B, Staels B, Chinetti-Gbaguidi G. Bories G, et al. Circ Res. 2013 Nov 8;113(11):1196-205. doi: 10.1161/CIRCRESAHA.113.301656. Epub 2013 Sep 13. Circ Res. 2013. PMID: 24036496 Free PMC article.
51 results