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Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario.
Chipuk JE, Bouchier-Hayes L, Green DR. Chipuk JE, et al. Cell Death Differ. 2006 Aug;13(8):1396-402. doi: 10.1038/sj.cdd.4401963. Epub 2006 May 19. Cell Death Differ. 2006. PMID: 16710362 Review.
Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription.
Chipuk JE, Maurer U, Green DR, Schuler M. Chipuk JE, et al. Cancer Cell. 2003 Nov;4(5):371-81. doi: 10.1016/s1535-6108(03)00272-1. Cancer Cell. 2003. PMID: 14667504
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis.
Chipuk JE, Kuwana T, Bouchier-Hayes L, Droin NM, Newmeyer DD, Schuler M, Green DR. Chipuk JE, et al. Science. 2004 Feb 13;303(5660):1010-4. doi: 10.1126/science.1092734. Science. 2004. PMID: 14963330
Cytoplasmic p53: bax and forward.
Chipuk JE, Green DR. Chipuk JE, et al. Cell Cycle. 2004 Apr;3(4):429-31. Epub 2004 Apr 1. Cell Cycle. 2004. PMID: 15020844
Do inducers of apoptosis trigger caspase-independent cell death?
Chipuk JE, Green DR. Chipuk JE, et al. Nat Rev Mol Cell Biol. 2005 Mar;6(3):268-75. doi: 10.1038/nrm1573. Nat Rev Mol Cell Biol. 2005. PMID: 15714200 Review.
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR, Newmeyer DD. Kuwana T, et al. Among authors: chipuk je. Mol Cell. 2005 Feb 18;17(4):525-35. doi: 10.1016/j.molcel.2005.02.003. Mol Cell. 2005. PMID: 15721256
PUMA couples the nuclear and cytoplasmic proapoptotic function of p53.
Chipuk JE, Bouchier-Hayes L, Kuwana T, Newmeyer DD, Green DR. Chipuk JE, et al. Science. 2005 Sep 9;309(5741):1732-5. doi: 10.1126/science.1114297. Science. 2005. PMID: 16151013
Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis.
Spierings D, McStay G, Saleh M, Bender C, Chipuk J, Maurer U, Green DR. Spierings D, et al. Science. 2005 Oct 7;310(5745):66-7. doi: 10.1126/science.1117105. Science. 2005. PMID: 16210526
Dissecting p53-dependent apoptosis.
Chipuk JE, Green DR. Chipuk JE, et al. Cell Death Differ. 2006 Jun;13(6):994-1002. doi: 10.1038/sj.cdd.4401908. Cell Death Differ. 2006. PMID: 16543937 Review.
p53 and metabolism: Inside the TIGAR.
Green DR, Chipuk JE. Green DR, et al. Among authors: chipuk je. Cell. 2006 Jul 14;126(1):30-2. doi: 10.1016/j.cell.2006.06.032. Cell. 2006. PMID: 16839873 Review.
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