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High specificity in response of the sodium-dependent multivitamin transporter to derivatives of pantothenic acid.
Curr Top Med Chem. 2013;13(7):837-42. doi: 10.2174/1568026611313070006.
Curr Top Med Chem. 2013.
PMID: 23578027
Review.
Undesired versus designed enzymatic cleavage of linkers for liver targeting.
Chirapu SR, Bauman JN, Eng H, Goosen TC, Strelevitz TJ, Sinha SC, Dow RL, Finn MG.
Chirapu SR, et al.
Bioorg Med Chem Lett. 2014 Feb 15;24(4):1144-7. doi: 10.1016/j.bmcl.2013.12.126. Epub 2014 Jan 8.
Bioorg Med Chem Lett. 2014.
PMID: 24461291
Free PMC article.
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Hepatitis B Virus Capsids Have Diverse Structural Responses to Small-Molecule Ligands Bound to the Heteroaryldihydropyrimidine Pocket.
Venkatakrishnan B, Katen SP, Francis S, Chirapu S, Finn MG, Zlotnick A.
Venkatakrishnan B, et al.
J Virol. 2016 Mar 28;90(8):3994-4004. doi: 10.1128/JVI.03058-15. Print 2016 Apr.
J Virol. 2016.
PMID: 26842475
Free PMC article.
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Phase diagrams map the properties of antiviral agents directed against hepatitis B virus core assembly.
Li L, Chirapu SR, Finn MG, Zlotnick A.
Li L, et al. Among authors: chirapu sr.
Antimicrob Agents Chemother. 2013 Mar;57(3):1505-8. doi: 10.1128/AAC.01766-12. Epub 2012 Dec 3.
Antimicrob Agents Chemother. 2013.
PMID: 23208717
Free PMC article.
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Assembly-directed antivirals differentially bind quasiequivalent pockets to modify hepatitis B virus capsid tertiary and quaternary structure.
Katen SP, Tan Z, Chirapu SR, Finn MG, Zlotnick A.
Katen SP, et al. Among authors: chirapu sr.
Structure. 2013 Aug 6;21(8):1406-16. doi: 10.1016/j.str.2013.06.013. Epub 2013 Jul 18.
Structure. 2013.
PMID: 23871485
Free PMC article.
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Trapping of hepatitis B virus capsid assembly intermediates by phenylpropenamide assembly accelerators.
Katen SP, Chirapu SR, Finn MG, Zlotnick A.
Katen SP, et al. Among authors: chirapu sr.
ACS Chem Biol. 2010 Dec 17;5(12):1125-36. doi: 10.1021/cb100275b. Epub 2010 Oct 4.
ACS Chem Biol. 2010.
PMID: 20845949
Free PMC article.
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Molecular modeling, synthesis, and activity studies of novel biaryl and fused-ring BACE1 inhibitors.
Chirapu SR, Pachaiyappan B, Nural HF, Cheng X, Yuan H, Lankin DC, Abdul-Hay SO, Thatcher GR, Shen Y, Kozikowski AP, Petukhov PA.
Chirapu SR, et al.
Bioorg Med Chem Lett. 2009 Jan 1;19(1):264-74. doi: 10.1016/j.bmcl.2008.10.096. Epub 2008 Oct 25.
Bioorg Med Chem Lett. 2009.
PMID: 19013792
Free PMC article.
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