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Molecular insights into cancer therapeutic effects of the dietary medicinal phytochemical withaferin A.
Chirumamilla CS, Pérez-Novo C, Van Ostade X, Vanden Berghe W. Chirumamilla CS, et al. Proc Nutr Soc. 2017 May;76(2):96-105. doi: 10.1017/S0029665116002937. Epub 2017 Feb 6. Proc Nutr Soc. 2017. PMID: 28162105 Review.
Epigenetic strategies to reverse drug resistance in heterogeneous multiple myeloma.
Issa ME, Takhsha FS, Chirumamilla CS, Perez-Novo C, Vanden Berghe W, Cuendet M. Issa ME, et al. Among authors: chirumamilla cs. Clin Epigenetics. 2017 Feb 10;9:17. doi: 10.1186/s13148-017-0319-5. eCollection 2017. Clin Epigenetics. 2017. PMID: 28203307 Free PMC article. Review.
Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway.
Heyninck K, Sabbe L, Chirumamilla CS, Szarc Vel Szic K, Vander Veken P, Lemmens KJA, Lahtela-Kakkonen M, Naulaerts S, Op de Beeck K, Laukens K, Van Camp G, Weseler AR, Bast A, Haenen GRMM, Haegeman G, Vanden Berghe W. Heyninck K, et al. Among authors: chirumamilla cs. Biochem Pharmacol. 2016 Jun 1;109:48-61. doi: 10.1016/j.bcp.2016.03.026. Epub 2016 Apr 1. Biochem Pharmacol. 2016. PMID: 27045103
Selective Glucocorticoid Receptor Properties of GSK866 Analogs with Cysteine Reactive Warheads.
Chirumamilla CS, Palagani A, Kamaraj B, Declerck K, Verbeek MWC, Oksana R, De Bosscher K, Bougarne N, Ruttens B, Gevaert K, Houtman R, De Vos WH, Joossens J, Van Der Veken P, Augustyns K, Van Ostade X, Bogaerts A, De Winter H, Vanden Berghe W. Chirumamilla CS, et al. Front Immunol. 2017 Nov 1;8:1324. doi: 10.3389/fimmu.2017.01324. eCollection 2017. Front Immunol. 2017. PMID: 29163463 Free PMC article.
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma.
Hassannia B, Wiernicki B, Ingold I, Qu F, Van Herck S, Tyurina YY, Bayır H, Abhari BA, Angeli JPF, Choi SM, Meul E, Heyninck K, Declerck K, Chirumamilla CS, Lahtela-Kakkonen M, Van Camp G, Krysko DV, Ekert PG, Fulda S, De Geest BG, Conrad M, Kagan VE, Vanden Berghe W, Vandenabeele P, Vanden Berghe T. Hassannia B, et al. Among authors: chirumamilla cs. J Clin Invest. 2018 Aug 1;128(8):3341-3355. doi: 10.1172/JCI99032. Epub 2018 Jun 25. J Clin Invest. 2018. PMID: 29939160 Free PMC article.
Imidazo[2,1-b]benzothiazol Derivatives as Potential Allosteric Inhibitors of the Glucocorticoid Receptor.
Christodoulou MS, Dapiaggi F, Ghiringhelli F, Pieraccini S, Sironi M, Lucafò M, Curci D, Decorti G, Stocco G, Chirumamilla CS, Vanden Berghe W, Balaguer P, Michel BY, Burger A, Beccalli EM, Passarella D, Martinet N. Christodoulou MS, et al. Among authors: chirumamilla cs. ACS Med Chem Lett. 2018 Feb 26;9(4):339-344. doi: 10.1021/acsmedchemlett.7b00527. eCollection 2018 Apr 12. ACS Med Chem Lett. 2018. PMID: 29670697 Free PMC article.
Profiling Activity of Cellular Kinases in Migrating T-Cells.
Chirumamilla CS, Fazil MHUT, Perez-Novo C, Rangarajan S, de Wijn R, Ramireddy P, Verma NK, Vanden Berghe W. Chirumamilla CS, et al. Methods Mol Biol. 2019;1930:99-113. doi: 10.1007/978-1-4939-9036-8_13. Methods Mol Biol. 2019. PMID: 30610604
A systems biology network analysis of nutri(epi)genomic changes in endothelial cells exposed to epicatechin metabolites.
Milenkovic D, Berghe WV, Morand C, Claude S, van de Sandt A, Gorressen S, Monfoulet LE, Chirumamilla CS, Declerck K, Szic KSV, Lahtela-Kakkonen M, Gerhauser C, Merx MW, Kelm M. Milenkovic D, et al. Among authors: chirumamilla cs. Sci Rep. 2018 Oct 19;8(1):15487. doi: 10.1038/s41598-018-33959-x. Sci Rep. 2018. PMID: 30341379 Free PMC article.
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