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Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells.
Chitchumroonchokchai C, Bomser JA, Glamm JE, Failla ML. Chitchumroonchokchai C, et al. J Nutr. 2004 Dec;134(12):3225-32. doi: 10.1093/jn/134.12.3225. J Nutr. 2004. PMID: 15570017
Pretreatment with the xanthophylls and alpha-TC also inhibited UVB-induced activation of c-JUN NH(2)-terminal kinase (JNK) and p38 by 50-60 and 25-32%, respectively. ...
Pretreatment with the xanthophylls and alpha-TC also inhibited UVB-induced activation of c-JUN NH(2)-terminal kinase (JNK) and p38 by …
Assessment of lutein bioavailability from meals and a supplement using simulated digestion and caco-2 human intestinal cells.
Chitchumroonchokchai C, Schwartz SJ, Failla ML. Chitchumroonchokchai C, et al. J Nutr. 2004 Sep;134(9):2280-6. doi: 10.1093/jn/134.9.2280. J Nutr. 2004. PMID: 15333717
Hydrolysis of zeaxanthin esters by carboxyl ester lipase during digestion facilitates micellarization and uptake of the xanthophyll by Caco-2 human intestinal cells.
Chitchumroonchokchai C, Failla ML. Chitchumroonchokchai C, et al. J Nutr. 2006 Mar;136(3):588-94. doi: 10.1093/jn/136.3.588. J Nutr. 2006. PMID: 16484529
Iron and zinc supplementation improved iron and zinc status, but not physical growth, of apparently healthy, breast-fed infants in rural communities of northeast Thailand.
Wasantwisut E, Winichagoon P, Chitchumroonchokchai C, Yamborisut U, Boonpraderm A, Pongcharoen T, Sranacharoenpong K, Russameesopaphorn W. Wasantwisut E, et al. Among authors: chitchumroonchokchai c. J Nutr. 2006 Sep;136(9):2405-11. doi: 10.1093/jn/136.9.2405. J Nutr. 2006. PMID: 16920862 Clinical Trial.
In vitro micellarization and intestinal cell uptake of cis isomers of lycopene exceed those of all-trans lycopene.
Failla ML, Chitchumroonchokchai C, Ishida BK. Failla ML, et al. Among authors: chitchumroonchokchai c. J Nutr. 2008 Mar;138(3):482-6. doi: 10.1093/jn/138.3.482. J Nutr. 2008. PMID: 18287353
Xanthones from mangosteen prevent lipopolysaccharide-mediated inflammation and insulin resistance in primary cultures of human adipocytes.
Bumrungpert A, Kalpravidh RW, Chitchumroonchokchai C, Chuang CC, West T, Kennedy A, McIntosh M. Bumrungpert A, et al. Among authors: chitchumroonchokchai c. J Nutr. 2009 Jun;139(6):1185-91. doi: 10.3945/jn.109.106617. Epub 2009 Apr 29. J Nutr. 2009. PMID: 19403722
Moreover, alpha- and gamma-MG attenuated LPS activation of the mitogen-activated protein kinases (MAPK) c-jun NH(2)-terminal kinase, extracellular signal-related kinase, and p38. alpha- and gamma-MG also attenuated LPS activation of c-Jun and activator protein (AP)- …
Moreover, alpha- and gamma-MG attenuated LPS activation of the mitogen-activated protein kinases (MAPK) c-jun NH(2)-terminal kinase, …
Bioaccessibility, biotransformation, and transport of alpha-mangostin from Garcinia mangostana (Mangosteen) using simulated digestion and Caco-2 human intestinal cells.
Bumrungpert A, Kalpravidh RW, Suksamrarn S, Chaivisuthangkura A, Chitchumroonchokchai C, Failla ML. Bumrungpert A, et al. Among authors: chitchumroonchokchai c. Mol Nutr Food Res. 2009 May;53 Suppl 1:S54-61. doi: 10.1002/mnfr.200800260. Mol Nutr Food Res. 2009. PMID: 19415666
Xanthones in mangosteen juice are absorbed and partially conjugated by healthy adults.
Chitchumroonchokchai C, Riedl KM, Suksumrarn S, Clinton SK, Kinghorn AD, Failla ML. Chitchumroonchokchai C, et al. J Nutr. 2012 Apr;142(4):675-80. doi: 10.3945/jn.111.156992. Epub 2012 Mar 7. J Nutr. 2012. PMID: 22399525 Free PMC article. Clinical Trial.
The juice provided 5.3 ± 0.1 mmol/L total xanthones with α-mangostin, garcinones (C, D, and E), γ-mangostin, gartanins, and other identified xanthones accounting for 58, 2, 6, 4, and 5%, respectively. ...
The juice provided 5.3 ± 0.1 mmol/L total xanthones with α-mangostin, garcinones (C, D, and E), γ-mangostin, gartanins, and other ide …
Anti-tumorigenicity of dietary α-mangostin in an HT-29 colon cell xenograft model and the tissue distribution of xanthones and their phase II metabolites.
Chitchumroonchokchai C, Thomas-Ahner JM, Li J, Riedl KM, Nontakham J, Suksumrarn S, Clinton SK, Kinghorn AD, Failla ML. Chitchumroonchokchai C, et al. Mol Nutr Food Res. 2013 Feb;57(2):203-11. doi: 10.1002/mnfr.201200539. Epub 2012 Dec 13. Mol Nutr Food Res. 2013. PMID: 23239542 Free PMC article.
METHODS AND RESULTS: Balb/c nu/nu mice were fed either control diet or diet containing 900 mg α-MG/kg. After 1 week of acclimation to diet, mice were injected subcutaneously with HT-29 cells and fed the same diets ad libitum for an additional 2 or 4 weeks. ...
METHODS AND RESULTS: Balb/c nu/nu mice were fed either control diet or diet containing 900 mg α-MG/kg. After 1 week of acclimation to …
α-Mangostin: anti-inflammatory activity and metabolism by human cells.
Gutierrez-Orozco F, Chitchumroonchokchai C, Lesinski GB, Suksamrarn S, Failla ML. Gutierrez-Orozco F, et al. Among authors: chitchumroonchokchai c. J Agric Food Chem. 2013 Apr 24;61(16):3891-900. doi: 10.1021/jf4004434. Epub 2013 Apr 11. J Agric Food Chem. 2013. PMID: 23578285 Free PMC article.
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