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Brain penetration of aprepitant, a substance P receptor antagonist, in ferrets.
Huskey SE, Dean BJ, Bakhtiar R, Sanchez RI, Tattersall FD, Rycroft W, Hargreaves R, Watt AP, Chicchi GG, Keohane C, Hora DF, Chiu SH. Huskey SE, et al. Among authors: chiu sh. Drug Metab Dispos. 2003 Jun;31(6):785-91. doi: 10.1124/dmd.31.6.785. Drug Metab Dispos. 2003. PMID: 12756213
Metabolism of a thiazole benzenesulfonamide derivative, a potent and elective agonist of the human beta3-adrenergic receptor, in rats: identification of a novel isethionic acid conjugate.
Tang W, Stearns RA, Miller RR, Ngui JS, Mathvink RJ, Weber AE, Kwei GY, Strauss JR, Keohane CA, Doss GA, Chiu SH, Baillie TA. Tang W, et al. Among authors: chiu sh. Drug Metab Dispos. 2002 Jul;30(7):778-87. doi: 10.1124/dmd.30.7.778. Drug Metab Dispos. 2002. PMID: 12065436
Identification of metabolites of a substance P (neurokinin 1 receptor) antagonist in rat hepatocytes and rat plasma.
Hop CE, Wang Y, Kumar S, Elipe MV, Raab CE, Dean DC, Poon GK, Keohane CA, Strauss J, Chiu SH, Curtis N, Elliott J, Gerhard U, Locker K, Morrison D, Mortishire-Smith R, Thomas S, Watt AP, Evans DC. Hop CE, et al. Among authors: chiu sh. Drug Metab Dispos. 2002 Aug;30(8):937-43. doi: 10.1124/dmd.30.8.937. Drug Metab Dispos. 2002. PMID: 12124313
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