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Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, Mei L, Nicolae DL, Regueiro M, Schumm LP, Steinhart AH, Rotter JI, Duerr RH, Cho JH, Daly MJ, Brant SR. Rioux JD, et al. Among authors: cho jh. Nat Genet. 2007 May;39(5):596-604. doi: 10.1038/ng2032. Epub 2007 Apr 15. Nat Genet. 2007. PMID: 17435756 Free PMC article.
MDR1 Ala893 polymorphism is associated with inflammatory bowel disease.
Brant SR, Panhuysen CI, Nicolae D, Reddy DM, Bonen DK, Karaliukas R, Zhang L, Swanson E, Datta LW, Moran T, Ravenhill G, Duerr RH, Achkar JP, Karban AS, Cho JH. Brant SR, et al. Among authors: cho jh. Am J Hum Genet. 2003 Dec;73(6):1282-92. doi: 10.1086/379927. Epub 2003 Nov 7. Am J Hum Genet. 2003. PMID: 14610718 Free PMC article.
Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis.
Karban AS, Okazaki T, Panhuysen CI, Gallegos T, Potter JJ, Bailey-Wilson JE, Silverberg MS, Duerr RH, Cho JH, Gregersen PK, Wu Y, Achkar JP, Dassopoulos T, Mezey E, Bayless TM, Nouvet FJ, Brant SR. Karban AS, et al. Among authors: cho jh. Hum Mol Genet. 2004 Jan 1;13(1):35-45. doi: 10.1093/hmg/ddh008. Epub 2003 Nov 12. Hum Mol Genet. 2004. PMID: 14613970
The IBD international genetics consortium provides further evidence for linkage to IBD4 and shows gene-environment interaction.
Pierik M, Yang H, Barmada MM, Cavanaugh JA, Annese V, Brant SR, Cho JH, Duerr RH, Hugot JP, McGovern DP, Paavola-Sakki P, Radford-Smith GL, Pavli P, Silverberg MS, Schreiber S, Taylor KD, Vlietinck R; IBD International Genetics Consortium. Pierik M, et al. Among authors: cho jh. Inflamm Bowel Dis. 2005 Jan;11(1):1-7. doi: 10.1097/00054725-200501000-00001. Inflamm Bowel Dis. 2005. PMID: 15674107
4,070 results