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Endothelin-1 enhances the proliferation of normal human melanocytes in a paradoxical manner from the TNF-α-inhibited condition, but tacrolimus promotes exclusively the cellular migration without proliferation: a proposed action mechanism for combination therapy of phototherapy and topical tacrolimus in vitiligo treatment.
Lee KY, Jeon SY, Hong JW, Choi KW, Lee CY, Choi SJ, Kim JH, Song KH, Kim KH. Lee KY, et al. Among authors: choi kw, choi sj. J Eur Acad Dermatol Venereol. 2013 May;27(5):609-16. doi: 10.1111/j.1468-3083.2012.04498.x. Epub 2012 Mar 9. J Eur Acad Dermatol Venereol. 2013. PMID: 22404745
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