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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1947 1
1948 3
1949 2
1950 3
1951 1
1952 1
1953 2
1954 2
1955 1
1956 3
1957 3
1958 5
1959 10
1960 19
1961 9
1962 11
1963 33
1964 43
1965 23
1966 52
1967 94
1968 96
1969 122
1970 143
1971 140
1972 172
1973 187
1974 217
1975 174
1976 209
1977 201
1978 204
1979 211
1980 249
1981 302
1982 320
1983 358
1984 452
1985 545
1986 490
1987 443
1988 506
1989 605
1990 546
1991 513
1992 567
1993 568
1994 622
1995 479
1996 454
1997 492
1998 416
1999 392
2000 366
2001 350
2002 301
2003 341
2004 350
2005 301
2006 315
2007 338
2008 302
2009 263
2010 301
2011 291
2012 289
2013 273
2014 228
2015 198
2016 201
2017 209
2018 172
2019 178
2020 198
2021 176
2022 307
2023 197
2024 162
2025 149
2026 88

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17,825 results

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Page 1
Cholecystokinin (CCK) and related adjunct peptide therapies for the treatment of obesity and type 2 diabetes.
Pathak V, Flatt PR, Irwin N. Pathak V, et al. Peptides. 2018 Feb;100:229-235. doi: 10.1016/j.peptides.2017.09.007. Peptides. 2018. PMID: 29412823 Review.
Cholecystokinin (CCK) is a hormone secreted from I-cells of the gut, as well as neurons in the enteric and central nervous system, that binds and activates CCK-1 and CCK-2 receptors to mediate its biological actions. ...Consequently, this has led to th …
Cholecystokinin (CCK) is a hormone secreted from I-cells of the gut, as well as neurons in the enteric and central nervous sys …
Cholecystokinin - portrayal of an unfolding peptide messenger system.
Rehfeld JF. Rehfeld JF. Peptides. 2025 Apr;186:171369. doi: 10.1016/j.peptides.2025.171369. Epub 2025 Feb 19. Peptides. 2025. PMID: 39983917 Free article. Review.
This review describes how the classic gut hormone, cholecystokinin (CCK), should be comprehended in 2025. In the early physiological tradition of studying gastrointestinal hormones, the hormones were named after the function that lead to their discovery. ...Today, t …
This review describes how the classic gut hormone, cholecystokinin (CCK), should be comprehended in 2025. In the early physiol …
Cholecystokinin/sulfakinin peptide signaling: conserved roles at the intersection between feeding, mating and aggression.
Nässel DR, Wu SF. Nässel DR, et al. Cell Mol Life Sci. 2022 Mar 14;79(3):188. doi: 10.1007/s00018-022-04214-4. Cell Mol Life Sci. 2022. PMID: 35286508 Free PMC article. Review.
Some neuropeptides and their cognate receptors are structurally and functionally well conserved over evolution in bilaterian animals. Among these are peptides related to gastrin and cholecystokinin (CCK). In mammals, CCK is produced by intestinal endoc …
Some neuropeptides and their cognate receptors are structurally and functionally well conserved over evolution in bilaterian animals. Among …
Cholecystokinin (CCK) and vasoactive intestinal peptide (VIP) in the cerebral cortex of the non-hibernating and hibernating golden mantled ground squirrel.
Bauman WA, Meryn S, Florant GL. Bauman WA, et al. Comp Biochem Physiol A Comp Physiol. 1988;91(1):179-81. doi: 10.1016/0300-9629(88)91613-1. Comp Biochem Physiol A Comp Physiol. 1988. PMID: 2904329
The effect of hibernation on cerebral cortical concentrations of cholecystokinin and vasoactive intestinal peptide was investigated in the golden mantled ground squirrel (Citellus lateralis). 2. ...The molecular forms of CCK appeared the same both before and …
The effect of hibernation on cerebral cortical concentrations of cholecystokinin and vasoactive intestinal peptide was investi …
Exploring FDA-Approved Frontiers: Insights into Natural and Engineered Peptide Analogues in the GLP-1, GIP, GHRH, CCK, ACTH, and alpha-MSH Realms.
Al Musaimi O. Al Musaimi O. Biomolecules. 2024 Feb 22;14(3):264. doi: 10.3390/biom14030264. Biomolecules. 2024. PMID: 38540684 Free PMC article. Review.
Peptides continue to gain significance in the pharmaceutical arena. Since the unveiling of insulin in 1921, the Food and Drug Administration (FDA) has authorised around 100 peptides for various applications. ...In this review, I analyse the FDA approval of natural …
Peptides continue to gain significance in the pharmaceutical arena. Since the unveiling of insulin in 1921, the Food and Drug Adminis …
Recombinant prohormone convertase 1 and 2 cleave purified pro cholecystokinin (CCK) and a synthetic peptide containing CCK 8 Gly Arg Arg and the carboxyl-terminal flanking peptide.
Tagen MB, Beinfeld MC. Tagen MB, et al. Peptides. 2005 Dec;26(12):2530-5. doi: 10.1016/j.peptides.2005.05.006. Epub 2005 Jun 24. Peptides. 2005. PMID: 15979761
Purified recombinant prohormone convertase 1 and 2 (PC1 and PC2) cleave a peptide containing cholecystokinin (CCK) 8 Gly Arg Arg and the carboxyl-terminal peptide liberating CCK 8 Gly Arg Arg. PC1 and PC2 also cleave purified pro CCK, lib …
Purified recombinant prohormone convertase 1 and 2 (PC1 and PC2) cleave a peptide containing cholecystokinin (CCK) 8 Gl …
Vagal afferent cholecystokinin receptor activation is required for glucagon-like peptide-1-induced satiation.
Vana V, Laerke MK, Rehfeld JF, Arnold M, Dmytriyeva O, Langhans W, Schwartz TW, Hansen HS. Vana V, et al. Diabetes Obes Metab. 2022 Feb;24(2):268-280. doi: 10.1111/dom.14575. Epub 2021 Nov 21. Diabetes Obes Metab. 2022. PMID: 34658116
Peripheral glucagon-like peptide-1 (GLP-1) and cholecystokinin (CCK) are secreted from enteroendocrine cells, and their plasma concentrations increase in response to eating. ...We therefore hypothesized that other gut peptides released during a meal mi …
Peripheral glucagon-like peptide-1 (GLP-1) and cholecystokinin (CCK) are secreted from enteroendocrine cells, and their …
Phylogeny of the cholecystokinin/gastrin family.
Johnsen AH. Johnsen AH. Front Neuroendocrinol. 1998 Apr;19(2):73-99. doi: 10.1006/frne.1997.0163. Front Neuroendocrinol. 1998. PMID: 9578981 Review.
The neuroendocrine peptides cholecystokinin (CCK) and gastrin, originally identified in mammals, are characterized by a common amidated C-terminal tetrapeptide sequence, Trp-Met-Asp-Phe.NH2, which also constitutes the minimal structure necessary for biologica …
The neuroendocrine peptides cholecystokinin (CCK) and gastrin, originally identified in mammals, are characterized by a …
Cholecystokinin regulates atrial natriuretic peptide secretion through activation of NOX4-Sirt1-LEF1 signaling in beating rat hypoxic atria.
Xu LJ, Zhi MT, Lin XX, Li X, Li ZY, Cui X. Xu LJ, et al. Peptides. 2024 Nov;181:171299. doi: 10.1016/j.peptides.2024.171299. Epub 2024 Sep 24. Peptides. 2024. PMID: 39326462
The mammalian cardiac myocytes not only synthesize and secrete atrial natriuretic peptide (ANP), but also express cholecystokinin (CCK) and its receptors (CCK(1)R and CCK(2)R). ...The results of this study showed that acute hypoxia significantly …
The mammalian cardiac myocytes not only synthesize and secrete atrial natriuretic peptide (ANP), but also express cholecystokinin …
Cholecystokinin (CCK) and its receptors (CCK1R and CCK2R) in chickens: functional analysis and tissue expression.
Wan Y, Deng Q, Zhou Z, Deng Y, Zhang J, Li J, Wang Y. Wan Y, et al. Poult Sci. 2023 Jan;102(1):102273. doi: 10.1016/j.psj.2022.102273. Epub 2022 Oct 22. Poult Sci. 2023. PMID: 36436379 Free PMC article.
Cholecystokinin (CCK) is widely distributed in the gastrointestinal tract and central nervous system, regulating a range of physiological functions by activating its receptors (CCK1R and CCK2R). ...Our data reveal the differential specificities of CCK recepto …
Cholecystokinin (CCK) is widely distributed in the gastrointestinal tract and central nervous system, regulating a range of ph …
17,825 results
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