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4,856 results

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Page 1
Binding of cholecystokinin-8 (CCK-8) peptide derivatives to CCKA and CCKB receptors.
Schäfer U, Harhammer R, Boomgaarden M, Sohr R, Ott T, Henklein P, Repke H. Schäfer U, et al. J Neurochem. 1994 Apr;62(4):1426-31. doi: 10.1046/j.1471-4159.1994.62041426.x. J Neurochem. 1994. PMID: 8133271
The structural requirements for the selective binding of cholecystokinin-8 (CCK-8)-related peptides to peripheral (CCKA) receptors are not sufficiently understood. In this study, the interaction of a series of newly shortened analogues of CCK- …
The structural requirements for the selective binding of cholecystokinin-8 (CCK-8)-related peptides to periphera …
Differential effects of cholecystokinin (CCK-8) microinjection into the ventrolateral and dorsolateral periaqueductal gray on anxiety models in Wistar rats.
Vázquez-León P, Campos-Rodríguez C, Gonzalez-Pliego C, Miranda-Páez A. Vázquez-León P, et al. Horm Behav. 2018 Nov;106:105-111. doi: 10.1016/j.yhbeh.2018.10.003. Epub 2018 Oct 19. Horm Behav. 2018. PMID: 30342011
The results on the DBB test confirmed an anxiolytic-like response of CCK-8 into the VL-PAG. In conclusion, CCK-8 microinjected into DL-PAG produced anxiety-like behavior on EPM, and for first time reported on DBB. Contrarily, CCK-8 microi …
The results on the DBB test confirmed an anxiolytic-like response of CCK-8 into the VL-PAG. In conclusion, CCK-8 …
CCK-58 prolongs the intermeal interval, whereas CCK-8 reduces this interval: not all forms of cholecystokinin have equal bioactivity.
Sayegh AI, Washington MC, Raboin SJ, Aglan AH, Reeve JR Jr. Sayegh AI, et al. Peptides. 2014 May;55:120-5. doi: 10.1016/j.peptides.2014.02.014. Epub 2014 Mar 4. Peptides. 2014. PMID: 24607725
We found that (1) all doses of CCK-58, except the lowest dose, and all doses of CCK-8, except the lowest two doses, reduced food intake more than vehicle did; (2) at two doses, 0.75 and 3 nmol/kg, CCK-58 increased the IMI, while CCK-8 failed to alter t …
We found that (1) all doses of CCK-58, except the lowest dose, and all doses of CCK-8, except the lowest two doses, reduced fo …
Bioactivity of cholecystokinin analogues: CCK-8 is not more potent than CCK-33.
Solomon TE, Yamada T, Elashoff J, Wood J, Beglinger C. Solomon TE, et al. Am J Physiol. 1984 Jul;247(1 Pt 1):G105-11. doi: 10.1152/ajpgi.1984.247.1.G105. Am J Physiol. 1984. PMID: 6204542
We determined the relative molar potencies of structural analogues of porcine cholecystokinin (CCK-39, CCK-33, CCK-8, and caerulein). Peptide concentrations delivered in infusates or present in bathing medium were measured by radioimmunoassay. ...Our data ind …
We determined the relative molar potencies of structural analogues of porcine cholecystokinin (CCK-39, CCK-33, CCK-8, a …
Effects of two cholecystokinin variants, CCK-39 and CCK-8, on basal and stimulated insulin secretion.
Ahrén B, Lundquist I. Ahrén B, et al. Acta Diabetol Lat. 1981 Oct-Dec;18(4):345-56. doi: 10.1007/BF02042819. Acta Diabetol Lat. 1981. PMID: 6277122
The effects of two different cholecystokinin variants, CCK-39 and the carboxyl-terminal octa-peptide CCK-8, on basal and stimulated insulin secretion were studied in the mouse. ...The calculated half-maximal dose was 2.12 nmol/kg for CCK-39 and 3.18 nmol/kg f …
The effects of two different cholecystokinin variants, CCK-39 and the carboxyl-terminal octa-peptide CCK-8, on basal an …
Non-sulfated cholecystokinin-8 increases enteric and hindbrain Fos-like immunoreactivity in male Sprague Dawley rats.
Dafalla AI, Mhalhal TR, Hiscocks K, Heath J, Sayegh AI. Dafalla AI, et al. Brain Res. 2019 Apr 1;1708:200-206. doi: 10.1016/j.brainres.2018.12.019. Epub 2018 Dec 17. Brain Res. 2019. PMID: 30571983 Free PMC article.
Recently, we reported that non-sulfated cholecystokinin-8 (NS CCK-8) reduces food intake by cholecystokinin-B receptors (CCK-BR). To examine a possible site of action for this peptide, and based on the fact that both NS CCK-8 and CCK-BR a …
Recently, we reported that non-sulfated cholecystokinin-8 (NS CCK-8) reduces food intake by cholecystokinin-B re …
The cholecystokinin analogues JMV-180 and CCK-8 stimulate phospholipase C through the same binding site of CCK(A) receptor in rat pancreatic acini.
Sarri E, Ramos B, Salido GM, Claro E. Sarri E, et al. Br J Pharmacol. 2001 Aug;133(8):1227-34. doi: 10.1038/sj.bjp.0704190. Br J Pharmacol. 2001. PMID: 11498507 Free PMC article.
However, since lithium blocks the phosphoinositide cycle by an uncompetitive mechanism, its effect was only apparent at high concentrations of CCK-8 (>10 pM), which elicited stimuli above 20 and 60% of the maximal [(32)P]-PtdOH and [(32)P]-PtdIns labelling, respe …
However, since lithium blocks the phosphoinositide cycle by an uncompetitive mechanism, its effect was only apparent at high concentrations …
Cholecystokinin(CCK)-A and CCK-B/gastrin receptors in human tumors.
Reubi JC, Schaer JC, Waser B. Reubi JC, et al. Cancer Res. 1997 Apr 1;57(7):1377-86. Cancer Res. 1997. PMID: 9102227
Cholecystokinin (CCK)-A and CCK-B/gastrin receptors were evaluated with in vitro receptor autoradiography in 406 human tumors of various origins using a sulfated 125I-labeled CCK decapeptide analogue 125I-(D-Tyr-Gly, Nle28,3l)-CCK 26-33 and 125I-labeled Leu15-gastrin as ra …
Cholecystokinin (CCK)-A and CCK-B/gastrin receptors were evaluated with in vitro receptor autoradiography in 406 human tumors of vari …
Molecular cloning of cholecystokinin (CCK) and CCK-A receptor and mechanism of CCK-induced gastrointestinal motility in Suncus murinus.
Takemi S, Honda W, Yokota N, Sekiya H, Miura T, Wada R, Sakai T, Sakata I. Takemi S, et al. Gen Comp Endocrinol. 2022 Oct 1;327:114074. doi: 10.1016/j.ygcen.2022.114074. Epub 2022 Jun 11. Gen Comp Endocrinol. 2022. PMID: 35700795
Suncus CCK mRNA and CCK-producing cells were found mainly in small intestine and colon. In the organ bath study, CCK-8 induced dose-dependent contractions in the suncus stomach, duodenum, and jejunum, and these contractions were inhibited by atropine and CCK-A recep …
Suncus CCK mRNA and CCK-producing cells were found mainly in small intestine and colon. In the organ bath study, CCK-8 induced …
4,856 results