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Epigenetic germline inheritance.
Chong S, Whitelaw E. Chong S, et al. Curr Opin Genet Dev. 2004 Dec;14(6):692-6. doi: 10.1016/j.gde.2004.09.001. Curr Opin Genet Dev. 2004. PMID: 15531166 Review.
Modifiers of epigenetic reprogramming show paternal effects in the mouse.
Chong S, Vickaryous N, Ashe A, Zamudio N, Youngson N, Hemley S, Stopka T, Skoultchi A, Matthews J, Scott HS, de Kretser D, O'Bryan M, Blewitt M, Whitelaw E. Chong S, et al. Nat Genet. 2007 May;39(5):614-22. doi: 10.1038/ng2031. Epub 2007 Apr 22. Nat Genet. 2007. PMID: 17450140 Free PMC article.
Transgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmission.
Rakyan VK, Chong S, Champ ME, Cuthbert PC, Morgan HD, Luu KV, Whitelaw E. Rakyan VK, et al. Among authors: chong s. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2538-43. doi: 10.1073/pnas.0436776100. Epub 2003 Feb 24. Proc Natl Acad Sci U S A. 2003. PMID: 12601169 Free PMC article.
How the mouse got its spots.
Blewitt ME, Chong S, Whitelaw E. Blewitt ME, et al. Among authors: chong s. Trends Genet. 2004 Nov;20(11):550-4. doi: 10.1016/j.tig.2004.08.011. Trends Genet. 2004. PMID: 15475114
One's ultimate phenotype is the result of a combination of genotype and environment, and includes a poorly understood component termed "developmental noise". ...
One's ultimate phenotype is the result of a combination of genotype and environment, and includes a poorly understood component terme …
Gene silencing is an ancient means of producing multiple phenotypes from the same genotype: common mechanisms and functions in epigenetic processes can be seen throughout all life forms.
Youngson NA, Chong S, Whitelaw E. Youngson NA, et al. Among authors: chong s. Bioessays. 2011 Feb;33(2):95-9. doi: 10.1002/bies.201000122. Bioessays. 2011. PMID: 21154782 No abstract available.
Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise.
Whitelaw NC, Chong S, Morgan DK, Nestor C, Bruxner TJ, Ashe A, Lambley E, Meehan R, Whitelaw E. Whitelaw NC, et al. Among authors: chong s. Genome Biol. 2010;11(11):R111. doi: 10.1186/gb-2010-11-11-r111. Epub 2010 Nov 19. Genome Biol. 2010. PMID: 21092094 Free PMC article.
Non-telomeric epigenetic and genetic changes are associated with the inheritance of shorter telomeres in mice.
Roberts AR, Huang E, Jones L, Daxinger L, Chong S, Whitelaw E. Roberts AR, et al. Among authors: chong s. Chromosoma. 2013 Dec;122(6):541-54. doi: 10.1007/s00412-013-0427-8. Epub 2013 Jul 18. Chromosoma. 2013. PMID: 23864360
DNMT3L is a regulator of X chromosome compaction and post-meiotic gene transcription.
Zamudio NM, Scott HS, Wolski K, Lo CY, Law C, Leong D, Kinkel SA, Chong S, Jolley D, Smyth GK, de Kretser D, Whitelaw E, O'Bryan MK. Zamudio NM, et al. Among authors: chong s. PLoS One. 2011 Mar 31;6(3):e18276. doi: 10.1371/journal.pone.0018276. PLoS One. 2011. PMID: 21483837 Free PMC article.
These data provide a potential mechanism for some cases of human Klinefelter's and Turner's syndromes....
These data provide a potential mechanism for some cases of human Klinefelter's and Turner's syndromes....
Epigenetic regulation in male germ cells.
Zamudio NM, Chong S, O'Bryan MK. Zamudio NM, et al. Among authors: chong s. Reproduction. 2008 Aug;136(2):131-46. doi: 10.1530/REP-07-0576. Epub 2008 May 30. Reproduction. 2008. PMID: 18515312 Review.
Epigenetic studies in Developmental Origins of Health and Disease: pitfalls and key considerations for study design and interpretation.
Yamada L, Chong S. Yamada L, et al. Among authors: chong s. J Dev Orig Health Dis. 2017 Feb;8(1):30-43. doi: 10.1017/S2040174416000507. Epub 2016 Sep 9. J Dev Orig Health Dis. 2017. PMID: 27609592 Review.
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