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Page 1
SINE compounds activate exportin 1 degradation through an allosteric mechanism.
Wing CE, Fung HYJ, Kwanten B, Cagatay T, Niesman AB, Jacquemyn M, Gharghabi M, Permentier B, Shakya B, Nandi R, Ready JM, Kashyap T, Shacham S, Landesman Y, Lapalombella R, Daelemans D, Chook YM. Wing CE, et al. Among authors: chook ym. Nat Chem Biol. 2025 Dec;21(12):2002-2013. doi: 10.1038/s41589-025-02058-0. Epub 2025 Nov 21. Nat Chem Biol. 2025. PMID: 41286136
The nuclear export receptor CRM1/XPO1 and its diverse cargoes.
Kehlenbach RH, Chook YM. Kehlenbach RH, et al. Among authors: chook ym. Trends Biochem Sci. 2025 Dec;50(12):1131-1144. doi: 10.1016/j.tibs.2025.09.003. Epub 2025 Sep 27. Trends Biochem Sci. 2025. PMID: 41016879 Free article. Review.
SINE compounds activate exportin-1 degradation via an allosteric mechanism.
Wing CE, Fung HYJ, Kwanten B, Cagatay T, Niesman AB, Jacquemyn M, Gharghabi M, Permentier B, Shakya B, Nandi R, Ready JM, Kashyap T, Shacham S, Landesman Y, Lapalombella R, Daelemans D, Chook YM. Wing CE, et al. Among authors: chook ym. bioRxiv [Preprint]. 2025 Jun 9:2024.10.07.617049. doi: 10.1101/2024.10.07.617049. bioRxiv. 2025. Update in: Nat Chem Biol. 2025 Dec;21(12):2002-2013. doi: 10.1038/s41589-025-02058-0. PMID: 39416201 Free PMC article. Updated. Preprint.
83 results