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Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: two parallel randomized, placebo-controlled, double-blind clinical trials.
Boffard KD, Riou B, Warren B, Choong PI, Rizoli S, Rossaint R, Axelsen M, Kluger Y; NovoSeven Trauma Study Group. Boffard KD, et al. Among authors: choong pi. J Trauma. 2005 Jul;59(1):8-15; discussion 15-8. doi: 10.1097/01.ta.0000171453.37949.b7. J Trauma. 2005. PMID: 16096533 Clinical Trial.
Cost-Effectiveness of Recombinant Activated Factor VII as Adjunctive Therapy for Bleeding Control in Severely Injured Trauma Patients in Germany.
Rossaint R, Christensen MC, Choong PI, Boffard KD, Riou B, Rizoli S, Kluger Y, Lefering R, Morris S; NovoSeven® Trauma Study Group. Rossaint R, et al. Among authors: choong pi. Eur J Trauma Emerg Surg. 2007 Oct;33(5):528-38. doi: 10.1007/s00068-007-6210-x. Epub 2007 Jul 20. Eur J Trauma Emerg Surg. 2007. PMID: 26814938
Prolonged prothrombin time after recombinant activated factor VII therapy in critically bleeding trauma patients is associated with adverse outcomes.
McMullin NR, Wade CE, Holcomb JB, Nielsen TG, Rossaint R, Riou B, Rizoli SB, Kluger Y, Choong PI, Warren B, Tortella BJ, Boffard KD; NovoSeven Trauma Study Group. McMullin NR, et al. Among authors: choong pi. J Trauma. 2010 Jul;69(1):60-9. doi: 10.1097/TA.0b013e3181e17260. J Trauma. 2010. PMID: 20622579 Clinical Trial.