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Randomized double blind trial of an ayurvedic plant derived formulation for treatment of rheumatoid arthritis.
Chopra A, Lavin P, Patwardhan B, Chitre D. Chopra A, et al. J Rheumatol. 2000 Jun;27(6):1365-72. J Rheumatol. 2000. PMID: 10852255 Clinical Trial.
OBJECTIVE: To evaluate RA-1, a standardized plant extract formulation, traditionally considered a safe, effective antiarthritic in the Asian-Indian Ayurvedic medicinal system. ...CONCLUSION: In a trial with sufficient power, RA-1 revealed efficacy that was no …
OBJECTIVE: To evaluate RA-1, a standardized plant extract formulation, traditionally considered a safe, effective antiarthriti …
Antiarthritic activity of a standardized, multiherbal, Ayurvedic formulation containing Boswellia serrata: in vitro studies on knee cartilage from osteoarthritis patients.
Sumantran VN, Joshi AK, Boddul S, Koppikar SJ, Warude D, Patwardhan B, Chopra A, Chandwaskar R, Wagh UV. Sumantran VN, et al. Phytother Res. 2011 Sep;25(9):1375-80. doi: 10.1002/ptr.3365. Epub 2011 Feb 24. Phytother Res. 2011. PMID: 25363757
This formulation also induced a transient antiinflammatory effect as measured by a reduction in the levels of nitric oxide released by explants. ...In summary, this report provides the first, direct, in vitro biochemical evidence of anti-arthritic activity a
This formulation also induced a transient antiinflammatory effect as measured by a reduction in the levels of nitric oxide rel …
Ayurvedic medicine and arthritis.
Chopra A. Chopra A. Rheum Dis Clin North Am. 2000 Feb;26(1):133-44, x. doi: 10.1016/s0889-857x(05)70127-7. Rheum Dis Clin North Am. 2000. PMID: 10680201 Review.
Similar short-term clinical response to high-dose versus low-dose methotrexate in monotherapy and combination therapy in patients with rheumatoid arthritis.
Bergstra SA, Allaart CF, van den Berg R, Chopra A, Govind N, Huizinga TWJ, Landewe RBM. Bergstra SA, et al. Arthritis Res Ther. 2017 Nov 22;19(1):258. doi: 10.1186/s13075-017-1468-9. Arthritis Res Ther. 2017. PMID: 29166919 Free PMC article.
BACKGROUND: Aiming at rapid decrease of disease activity, there has been a trend to start with higher doses of methotrexate (MTX) in patients newly diagnosed with rheumatoid arthritis (RA), both as monotherapy and in combination with other antirheumatic drugs. ...METHODS: …
BACKGROUND: Aiming at rapid decrease of disease activity, there has been a trend to start with higher doses of methotrexate (MTX) in …
Association of 17 Definitions of Remission with Functional Status in a Large Clinical Practice Cohort of Patients with Rheumatoid Arthritis.
Carvalho PD, Ferreira RJO, Landewé R, Vega-Morales D, Salomon-Escoto K, Veale DJ, Chopra A, da Silva JAP, Machado PM. Carvalho PD, et al. J Rheumatol. 2020 Jan;47(1):20-27. doi: 10.3899/jrheum.181286. Epub 2019 May 1. J Rheumatol. 2020. PMID: 31043552
CONCLUSION: The 17 definitions of remission confirmed their validity against physical function in a large international clinical practice setting. Achievement of remission according to any of the indices may be more important than the use of a specific index. A
CONCLUSION: The 17 definitions of remission confirmed their validity against physical function in a large international clinical prac …
In the absence of specific advice, what do patients eat and avoid? Results from a community based diet study in patients suffering from rheumatoid arthritis (RA) with a focus on potassium.
Kianifard T, Chopra A. Kianifard T, et al. Clin Nutr ESPEN. 2018 Dec;28:214-221. doi: 10.1016/j.clnesp.2018.07.008. Epub 2018 Aug 14. Clin Nutr ESPEN. 2018. PMID: 30390884
Rheumatoid arthritis (RA) is a painful disabling difficult to treat disease. Clinicians and guidelines invariably focus on drugs. ...We carried out a comprehensive analytical study in Indian (Asian) patients. METHODS: 141 consenting symptomatic chronic RA patients [ …
Rheumatoid arthritis (RA) is a painful disabling difficult to treat disease. Clinicians and guidelines invariably focus on drugs. ... …
Autoantibody status is not associated with early treatment response to first-line methotrexate in patients with early rheumatoid arthritis.
Dekkers JS, Bergstra SA, Chopra A, Tikly M, Fonseca JE, Salomon-Escoto K, Huizinga TWJ, van der Woude D. Dekkers JS, et al. Rheumatology (Oxford). 2019 Jan 1;58(1):149-153. doi: 10.1093/rheumatology/key263. Rheumatology (Oxford). 2019. PMID: 30204896
Implications of the noncoding RNAs in rheumatoid arthritis pathogenesis.
Mousavi MJ, Jamshidi A, Chopra A, Aslani S, Akhlaghi M, Mahmoudi M. Mousavi MJ, et al. J Cell Physiol. 2018 Jan;234(1):335-347. doi: 10.1002/jcp.26911. Epub 2018 Aug 1. J Cell Physiol. 2018. PMID: 30069877 Review.
Epigenetics refers to a set of regulatory mechanisms that affect gene expression, while the original sequence of the DNA remains unchanged. ...A bulk of studies has identified that ncRNAs might be divided into several subtypes. On the one hand, investigations have d …
Epigenetics refers to a set of regulatory mechanisms that affect gene expression, while the original sequence of the DNA remains unch …
Sex-associated Treatment Differences and Their Outcomes in Rheumatoid Arthritis: Results from the METEOR Register.
Bergstra SA, Allaart CF, Ramiro S, Chopra A, Govind N, Silva C, Murphy EA, Landewé RBM. Bergstra SA, et al. J Rheumatol. 2018 Oct;45(10):1361-1366. doi: 10.3899/jrheum.171176. Epub 2018 Jun 15. J Rheumatol. 2018. PMID: 29907672 Clinical Trial.
RESULTS: Women (n = 4393) more often started treatment with hydroxychloroquine, as monotherapy or in combination with methotrexate (MTX) or a glucocorticoid, and men (n = 1142) more often started treatment with MTX and/or sulfasalazine. ...Women had a statistically …
RESULTS: Women (n = 4393) more often started treatment with hydroxychloroquine, as monotherapy or in combination with methotrexate (MTX) or …
Evaluation of the joint distribution at disease presentation of patients with rheumatoid arthritis: a large study across continents.
Bergstra SA, Chopra A, Saluja M, Vega-Morales D, Govind N, Huizinga TWJ, van der Helm-van Mil A. Bergstra SA, et al. RMD Open. 2017 Dec 10;3(2):e000568. doi: 10.1136/rmdopen-2017-000568. eCollection 2017. RMD Open. 2017. PMID: 29299341 Free PMC article.
Therefore, we studied tender and swollen joint involvement in patients newly diagnosed with RA in four countries and performed a subanalysis within countries to assess whether the influence of autoantibody positivity affected disease expression. ...
Therefore, we studied tender and swollen joint involvement in patients newly diagnosed with RA in four countries and performed a suba …
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