Chou RC - Search Results

1

A highly sensitive tool for the assay of cytochrome P450 enzyme activity in rat, dog and man. Direct fluorescence monitoring of the deethylation of 7-ethoxy-4-trifluoromethylcoumarin.

Buters JT, Schiller CD, Chou RC. Buters JT, et al. Among authors: chou rc. Biochem Pharmacol. 1993 Nov 2;46(9):1577-84. doi: 10.1016/0006-2952(93)90326-r. Biochem Pharmacol. 1993. PMID: 8240414

2

A new extrapolation method from animals to man: application to a metabolized compound, mofarotene.

Lave T, Schmitt-Hoffmann AH, Coassolo P, Valles B, Ubeaud G, Ba B, Brandt R, Chou RC. Lave T, et al. Among authors: chou rc. Life Sci. 1995;56(26):PL473-8. doi: 10.1016/0024-3205(95)00234-w. Life Sci. 1995. PMID: 7791515

3

Preformulation approaches to improve the oral bioavailability of two novel piperidine renin inhibitors in dog.

Bittner B, Chou R, Schleimer M, Morgenroth B, Zell M, Lavé T. Bittner B, et al. Arzneimittelforschung. 2002;52(8):593-9. doi: 10.1055/s-0031-1299936. Arzneimittelforschung. 2002. PMID: 12236046

4

Absorption of tretinoin in rats and rabbits following oral and dermal application.

Chou R, Bürgin H, Schmitt G, Eggers H. Chou R, et al. Arzneimittelforschung. 1997 Apr;47(4):401-5. Arzneimittelforschung. 1997. PMID: 9150861

5

Mechanistic studies on the ethyl-esterification of acitretin by human liver preparations in vitro.

Schmitt-Hoffmann AH, Dittrich S, Saulnier E, Schenk P, Chou RC. Schmitt-Hoffmann AH, et al. Among authors: chou rc. Life Sci. 1995 Nov 17;57(26):PL407-12. doi: 10.1016/0024-3205(95)02246-6. Life Sci. 1995. PMID: 8847958

6

Interspecies scaling of bosentan, a new endothelin receptor antagonist and integration of in vitro data into allometric scaling.

Lave T, Coassolo P, Ubeaud G, Brandt R, Schmitt C, Dupin S, Jaeck D, Chou RC. Lave T, et al. Among authors: chou rc. Pharm Res. 1996 Jan;13(1):97-101. doi: 10.1023/a:1016037519116. Pharm Res. 1996. PMID: 8668687

7

Interspecies scaling of interferon disposition and comparison of allometric scaling with concentration-time transformations.

Lave T, Levet-Trafit B, Schmitt-Hoffmann AH, Morgenroth B, Richter W, Chou RC. Lave T, et al. Among authors: chou rc. J Pharm Sci. 1995 Nov;84(11):1285-90. doi: 10.1002/jps.2600841106. J Pharm Sci. 1995. PMID: 8587044 Clinical Trial.

8

Estimation of oral drug absorption in man based on intestine permeability in rats.

Levet-Trafit B, Gruyer MS, Marjanovic M, Chou RC. Levet-Trafit B, et al. Among authors: chou rc. Life Sci. 1996;58(24):PL359-63. doi: 10.1016/0024-3205(96)00224-x. Life Sci. 1996. PMID: 8649204

9

Pharmacokinetics of acitretin and etretinate.

Wiegand UW, Chou RC. Wiegand UW, et al. Among authors: chou rc. J Am Acad Dermatol. 1998 Aug;39(2 Pt 3):S25-33. doi: 10.1016/s0190-9622(98)70441-4. J Am Acad Dermatol. 1998. PMID: 9703120 Review. No abstract available.

10

Integration of in vitro data into allometric scaling to predict hepatic metabolic clearance in man: application to 10 extensively metabolized drugs.

Lave T, Dupin S, Schmitt C, Chou RC, Jaeck D, Coassolo P. Lave T, et al. Among authors: chou rc. J Pharm Sci. 1997 May;86(5):584-90. doi: 10.1021/js960440h. J Pharm Sci. 1997. PMID: 9145383

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