Hypoxia drives cardiac miRNAs and inflammation in the right and left ventricle.
Chouvarine P, Legchenko E, Geldner J, Riehle C, Hansmann G.
Chouvarine P, et al.
J Mol Med (Berl). 2019 Oct;97(10):1427-1438. doi: 10.1007/s00109-019-01817-6. Epub 2019 Jul 23.
J Mol Med (Berl). 2019.
PMID: 31338525
LV in Hx) identified nine hypoxia-regulated miRNAs: let-7e-5p, miR-29c-3p, miR-127-3p, miR-130a-3p, miR-146b-5p, miR-197-3p, miR-214-3p, miR-223-3p, and miR-451. Hypoxia downregulated miR-146b in the RV (p < 0.01) and, less so, in the LV (trend; p = 0.28). In sil
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LV in Hx) identified nine hypoxia-regulated miRNAs: let-7e-5p, miR-29c-3p, miR-127-3p, miR-130a-3p, miR-146b-5p, miR-197-3p, miR-214-3p, miR …