Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

1,541 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
A novel Aurora kinase A inhibitor MK-8745 predicts TPX2 as a therapeutic biomarker in non-Hodgkin lymphoma cell lines.
Chowdhury A, Chowdhury S, Tsai MY. Chowdhury A, et al. Among authors: chowdhury s. Leuk Lymphoma. 2012 Mar;53(3):462-71. doi: 10.3109/10428194.2011.619018. Epub 2011 Oct 24. Leuk Lymphoma. 2012. PMID: 21879811
In this study, we demonstrate that treatment with MK-8745, a novel Aurora-A specific inhibitor, leads to cell cycle arrest at the G2/M phase with accumulation of tetraploid nuclei followed by cell death in non-Hodgkin lymphoma (NHL) cell lines. ...Our results indica …
In this study, we demonstrate that treatment with MK-8745, a novel Aurora-A specific inhibitor, leads to cell cycle arrest at …
KIBRA regulates aurora kinase activity and is required for precise chromosome alignment during mitosis.
Zhang L, Iyer J, Chowdhury A, Ji M, Xiao L, Yang S, Chen Y, Tsai MY, Dong J. Zhang L, et al. Among authors: chowdhury a. J Biol Chem. 2012 Oct 5;287(41):34069-77. doi: 10.1074/jbc.M112.385518. Epub 2012 Aug 17. J Biol Chem. 2012. PMID: 22904328 Free PMC article.
We recently reported that KIBRA is phosphorylated by the mitotic kinases Aurora-A and -B. However, the role KIBRA plays in mitosis has not been established. ...We propose that the KIBRA-Aurora-Lats2 protein complexes form a novel axis that regulates precise mitosis. …
We recently reported that KIBRA is phosphorylated by the mitotic kinases Aurora-A and -B. However, the role KIBRA plays in mitosis ha …
Identification of a novel TGFβ/PKA signaling transduceome in mediating control of cell survival and metastasis in colon cancer.
Chowdhury S, Howell GM, Rajput A, Teggart CA, Brattain LE, Weber HR, Chowdhury A, Brattain MG. Chowdhury S, et al. Among authors: chowdhury a. PLoS One. 2011 May 3;6(5):e19335. doi: 10.1371/journal.pone.0019335. PLoS One. 2011. PMID: 21559296 Free PMC article.
Moreover, we have identified a novel TGFβ/PKA tumor suppressor pathway that acts directly on a known cell survival mechanism that responds to stress with the survivin/XIAP dependent inhibition of caspases that effect apoptosis. ...CONCLUSION/SIGNIFICANCE: This work …
Moreover, we have identified a novel TGFβ/PKA tumor suppressor pathway that acts directly on a known cell survival mechanism t …
Histone deacetylase inhibitor belinostat represses survivin expression through reactivation of transforming growth factor beta (TGFbeta) receptor II leading to cancer cell death.
Chowdhury S, Howell GM, Teggart CA, Chowdhury A, Person JJ, Bowers DM, Brattain MG. Chowdhury S, et al. Among authors: chowdhury a. J Biol Chem. 2011 Sep 2;286(35):30937-48. doi: 10.1074/jbc.M110.212035. Epub 2011 Jul 8. J Biol Chem. 2011. PMID: 21757750 Free PMC article.
Survivin is a cancer-associated gene that functions to promote cell survival, cell division, and angiogenesis and is a marker of poor prognosis. ...We observed that belinostat activated protein kinase A at early time points in a TGFβ signaling-dependen …
Survivin is a cancer-associated gene that functions to promote cell survival, cell division, and angiogenesis and is a marker …
Natural killer cell lymphoma shares strikingly similar molecular features with a group of non-hepatosplenic γδ T-cell lymphoma and is highly sensitive to a novel aurora kinase A inhibitor in vitro.
Iqbal J, Weisenburger DD, Chowdhury A, Tsai MY, Srivastava G, Greiner TC, Kucuk C, Deffenbacher K, Vose J, Smith L, Au WY, Nakamura S, Seto M, Delabie J, Berger F, Loong F, Ko YH, Sng I, Liu X, Loughran TP, Armitage J, Chan WC; International Peripheral T-cell Lymphoma Project. Iqbal J, et al. Among authors: chowdhury a. Leukemia. 2011 Feb;25(2):348-58. doi: 10.1038/leu.2010.255. Epub 2010 Nov 5. Leukemia. 2011. PMID: 21052088
The classifier also identified a set of γδ-PTCLs both in the ENKTL cases as well as in cases initially classified as PTCL-not otherwise specified. ...Targeted inhibition of two oncogenic pathways (AURKA and NOTCH-1) by small-molecular inhibitors induced significant growth …
The classifier also identified a set of γδ-PTCLs both in the ENKTL cases as well as in cases initially classified as PTCL-not otherwi …
Inorganic arsenic: A non-genotoxic carcinogen.
Cohen SM, Chowdhury A, Arnold LL. Cohen SM, et al. Among authors: chowdhury a. J Environ Sci (China). 2016 Nov;49:28-37. doi: 10.1016/j.jes.2016.04.015. Epub 2016 May 17. J Environ Sci (China). 2016. PMID: 28007178 Review.
If this continues for a long period of time, it can result in an increased risk of cancer. Arsenicals do not react with DNA. ...Overall, the data strongly supports a non-linear dose response for the effects of inorganic arsenic. In various in vitro and in vivo model …
If this continues for a long period of time, it can result in an increased risk of cancer. Arsenicals do not react with DNA. ...Overa …
Low-dose dose-response for reduced cell viability after exposure of human keratinocyte (HEK001) cells to arsenite.
Bogen KT, Arnold LL, Chowdhury A, Pennington KL, Cohen SM. Bogen KT, et al. Among authors: chowdhury a. Toxicol Rep. 2016 Dec 14;4:32-38. doi: 10.1016/j.toxrep.2016.12.003. eCollection 2017. Toxicol Rep. 2016. PMID: 28959622 Free PMC article.
Because of unexpected variation in viability response patterns, a two-stage DR analysis was used in which data on plate-specific viability (%), estimated as 100% times the ratio of measured viability in exposed to unexposed cells, were fit initially to a generalized …
Because of unexpected variation in viability response patterns, a two-stage DR analysis was used in which data on plate-specific viab …
Effect of polyhexamethylene biguanide on rat liver.
Chowdhury A, Arnold LL, Wang Z, Pennington KL, Dodmane P, Farragut-Cardoso AP, Klaunig JE, Cros D, Creppy EE, Cohen SM. Chowdhury A, et al. Toxicol Lett. 2018 Mar 15;285:94-103. doi: 10.1016/j.toxlet.2017.12.032. Epub 2018 Jan 2. Toxicol Lett. 2018. PMID: 29305328
The PHMB-induced rat hepatocellular tumors are unlikely to pose a human cancer risk. However, the actual MOA has not been determined....
The PHMB-induced rat hepatocellular tumors are unlikely to pose a human cancer risk. However, the actual MOA has not been determined. …
Utilising venom activity to infer dietary composition of the Kenyan horned viper (Bitis worthingtoni).
Youngman NJ, Chowdhury A, Zdenek CN, Coster K, Sundman E, Braun R, Fry BG. Youngman NJ, et al. Among authors: chowdhury a. Comp Biochem Physiol C Toxicol Pharmacol. 2020 Oct 26:108921. doi: 10.1016/j.cbpc.2020.108921. Online ahead of print. Comp Biochem Physiol C Toxicol Pharmacol. 2020. PMID: 33122136
Electrochemical detection of white spot syndrome virus with a silicone rubber disposable electrode composed of graphene quantum dots and gold nanoparticle-embedded polyaniline nanowires.
Takemura K, Satoh J, Boonyakida J, Park S, Chowdhury AD, Park EY. Takemura K, et al. Among authors: chowdhury ad. J Nanobiotechnology. 2020 Oct 27;18(1):152. doi: 10.1186/s12951-020-00712-4. J Nanobiotechnology. 2020. PMID: 33109213 Free PMC article.
1,541 results
Jump to page
Feedback