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T-helper type 2-driven inflammation defines major subphenotypes of asthma.
Woodruff PG, Modrek B, Choy DF, Jia G, Abbas AR, Ellwanger A, Koth LL, Arron JR, Fahy JV. Woodruff PG, et al. Among authors: choy df. Am J Respir Crit Care Med. 2009 Sep 1;180(5):388-95. doi: 10.1164/rccm.200903-0392OC. Epub 2009 May 29. Am J Respir Crit Care Med. 2009. PMID: 19483109 Free PMC article. Clinical Trial.
Lung gene expression in a rhesus allergic asthma model correlates with physiologic parameters of disease and exhibits common and distinct pathways with human asthma and a mouse asthma model.
Abbas AR, Jackman JK, Bullens SL, Davis SM, Choy DF, Fedorowicz G, Tan M, Truong BT, Gloria Meng Y, Diehl L, Miller LA, Schelegle ES, Hyde DM, Clark HF, Modrusan Z, Arron JR, Wu LC. Abbas AR, et al. Among authors: choy df. Am J Pathol. 2011 Oct;179(4):1667-80. doi: 10.1016/j.ajpath.2011.06.009. Epub 2011 Aug 3. Am J Pathol. 2011. PMID: 21819959 Free PMC article.
Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients.
Jia G, Erickson RW, Choy DF, Mosesova S, Wu LC, Solberg OD, Shikotra A, Carter R, Audusseau S, Hamid Q, Bradding P, Fahy JV, Woodruff PG, Harris JM, Arron JR; Bronchoscopic Exploratory Research Study of Biomarkers in Corticosteroid-refractory Asthma (BOBCAT) Study Group. Jia G, et al. Among authors: choy df. J Allergy Clin Immunol. 2012 Sep;130(3):647-654.e10. doi: 10.1016/j.jaci.2012.06.025. Epub 2012 Aug 1. J Allergy Clin Immunol. 2012. PMID: 22857879 Free PMC article.
Disconnect between sputum neutrophils and other measures of airway inflammation in asthma.
Arron JR, Choy DF, Laviolette M, Kelsen SG, Hatab A, Leigh R, Thomson NC, Bleecker ER, Olivenstein R, Avila PC, Jarjour NN, Castro M, Gauvreau GM, Good JT, Kline JN, Mansur A, Mayers I, Heaney LG, Hamid Q, Harris JM. Arron JR, et al. Among authors: choy df. Eur Respir J. 2014 Feb;43(2):627-9. doi: 10.1183/09031936.00117013. Epub 2013 Oct 31. Eur Respir J. 2014. PMID: 24176993 No abstract available.
Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma.
McGarvey LP, Butler CA, Stokesberry S, Polley L, McQuaid S, Abdullah H, Ashraf S, McGahon MK, Curtis TM, Arron J, Choy D, Warke TJ, Bradding P, Ennis M, Zholos A, Costello RW, Heaney LG. McGarvey LP, et al. J Allergy Clin Immunol. 2014 Mar;133(3):704-12.e4. doi: 10.1016/j.jaci.2013.09.016. Epub 2013 Nov 8. J Allergy Clin Immunol. 2014. PMID: 24210884
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