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Severe and mild mutations in cis for the methylenetetrahydrofolate reductase (MTHFR) gene, and description of five novel mutations in MTHFR.
Goyette P, Christensen B, Rosenblatt DS, Rozen R. Goyette P, et al. Among authors: christensen b. Am J Hum Genet. 1996 Dec;59(6):1268-75. Am J Hum Genet. 1996. PMID: 8940272 Free PMC article.
Spina bifida, folate metabolism, and dietary folate intake in a Northern Canadian aboriginal population.
Arbour L, Christensen B, Delormier T, Platt R, Gilfix B, Forbes P, Kovitch I, Morel J, Rozen R. Arbour L, et al. Among authors: christensen b. Int J Circumpolar Health. 2002 Nov;61(4):341-51. doi: 10.3402/ijch.v61i4.17492. Int J Circumpolar Health. 2002. PMID: 12546192
Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders.
Leclerc D, Campeau E, Goyette P, Adjalla CE, Christensen B, Ross M, Eydoux P, Rosenblatt DS, Rozen R, Gravel RA. Leclerc D, et al. Among authors: christensen b. Hum Mol Genet. 1996 Dec;5(12):1867-74. doi: 10.1093/hmg/5.12.1867. Hum Mol Genet. 1996. PMID: 8968737
Prenatal detection of chromosome aneuploidies in uncultured chorionic villus samples by FISH.
Bryndorf T, Christensen B, Vad M, Parner J, Carelli MP, Ward BE, Klinger KW, Bang J, Philip J. Bryndorf T, et al. Among authors: christensen b. Am J Hum Genet. 1996 Oct;59(4):918-26. Am J Hum Genet. 1996. PMID: 8808609 Free PMC article.
Effects of folate deficiency on embryonic development.
Christensen B, Rosenblatt DS. Christensen B, et al. Baillieres Clin Haematol. 1995 Sep;8(3):617-37. doi: 10.1016/s0950-3536(05)80223-9. Baillieres Clin Haematol. 1995. PMID: 8534964 Review.
Characterization of six novel mutations in the methylenetetrahydrofolate reductase (MTHFR) gene in patients with homocystinuria.
Sibani S, Christensen B, O'Ferrall E, Saadi I, Hiou-Tim F, Rosenblatt DS, Rozen R. Sibani S, et al. Among authors: christensen b. Hum Mutat. 2000;15(3):280-7. doi: 10.1002/(SICI)1098-1004(200003)15:3<280::AID-HUMU9>3.0.CO;2-I. Hum Mutat. 2000. PMID: 10679944
A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida.
Wilson A, Platt R, Wu Q, Leclerc D, Christensen B, Yang H, Gravel RA, Rozen R. Wilson A, et al. Among authors: christensen b. Mol Genet Metab. 1999 Aug;67(4):317-23. doi: 10.1006/mgme.1999.2879. Mol Genet Metab. 1999. PMID: 10444342
Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defects.
Christensen B, Arbour L, Tran P, Leclerc D, Sabbaghian N, Platt R, Gilfix BM, Rosenblatt DS, Gravel RA, Forbes P, Rozen R. Christensen B, et al. Am J Med Genet. 1999 May 21;84(2):151-7. doi: 10.1002/(sici)1096-8628(19990521)84:2<151::aid-ajmg12>3.0.co;2-t. Am J Med Genet. 1999. PMID: 10323741
Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease.
Christensen B, Frosst P, Lussier-Cacan S, Selhub J, Goyette P, Rosenblatt DS, Genest J Jr, Rozen R. Christensen B, et al. Arterioscler Thromb Vasc Biol. 1997 Mar;17(3):569-73. doi: 10.1161/01.atv.17.3.569. Arterioscler Thromb Vasc Biol. 1997. PMID: 9102178
A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity.
Weisberg I, Tran P, Christensen B, Sibani S, Rozen R. Weisberg I, et al. Among authors: christensen b. Mol Genet Metab. 1998 Jul;64(3):169-72. doi: 10.1006/mgme.1998.2714. Mol Genet Metab. 1998. PMID: 9719624
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