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Structural and mechanistic aspects influencing the ADAM10-mediated shedding of the prion protein.
Mol Neurodegener. 2018 Apr 6;13(1):18. doi: 10.1186/s13024-018-0248-6.
Mol Neurodegener. 2018.
PMID: 29625583
Free PMC article.
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies.
Linsenmeier L, Mohammadi B, Shafiq M, Frontzek K, Bär J, Shrivastava AN, Damme M, Song F, Schwarz A, Da Vela S, Massignan T, Jung S, Correia A, Schmitz M, Puig B, Hornemann S, Zerr I, Tatzelt J, Biasini E, Saftig P, Schweizer M, Svergun D, Amin L, Mazzola F, Varani L, Thapa S, Gilch S, Schätzl H, Harris DA, Triller A, Mikhaylova M, Aguzzi A, Altmeppen HC, Glatzel M.
Linsenmeier L, et al. Among authors: tatzelt j.
Sci Adv. 2021 Nov 26;7(48):eabj1826. doi: 10.1126/sciadv.abj1826. Epub 2021 Nov 24.
Sci Adv. 2021.
PMID: 34818048
Free PMC article.
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