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Senolytics reduce coronavirus-related mortality in old mice.
Camell CD, Yousefzadeh MJ, Zhu Y, Prata LGPL, Huggins MA, Pierson M, Zhang L, O'Kelly RD, Pirtskhalava T, Xun P, Ejima K, Xue A, Tripathi U, Espindola-Netto JM, Giorgadze N, Atkinson EJ, Inman CL, Johnson KO, Cholensky SH, Carlson TW, LeBrasseur NK, Khosla S, O'Sullivan MG, Allison DB, Jameson SC, Meves A, Li M, Prakash YS, Chiarella SE, Hamilton SE, Tchkonia T, Niedernhofer LJ, Kirkland JL, Robbins PD. Camell CD, et al. Science. 2021 Jul 16;373(6552):eabe4832. doi: 10.1126/science.abe4832. Epub 2021 Jun 8. Science. 2021. PMID: 34103349 Free PMC article.
GDF3 promotes adipose tissue macrophage-mediated inflammation via altered chromatin accessibility during aging.
Jang IH, Kruglov V, Cholensky SH, Smith DM, Carey A, Bai S, Nottoli T, Bernlohr DA, Camell CD. Jang IH, et al. Among authors: camell cd. bioRxiv [Preprint]. 2024 Sep 25:2024.09.23.614375. doi: 10.1101/2024.09.23.614375. bioRxiv. 2024. Update in: Nat Aging. 2026 Jan;6(1):127-142. doi: 10.1038/s43587-025-01034-6. PMID: 39386655 Free PMC article. Updated. Preprint.
The ageing immune system as a driver of systemic ageing.
Jang IH, Niedernhofer LJ, Robbins PD, Camell CD. Jang IH, et al. Among authors: camell cd. Nat Rev Immunol. 2026 Feb 13. doi: 10.1038/s41577-026-01269-3. Online ahead of print. Nat Rev Immunol. 2026. PMID: 41688787 Review.
27 results