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Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
Stieglitz B, Rana RR, Koliopoulos MG, Morris-Davies AC, Schaeffer V, Christodoulou E, Howell S, Brown NR, Dikic I, Rittinger K. Stieglitz B, et al. Among authors: christodoulou e. Nature. 2013 Nov 21;503(7476):422-426. doi: 10.1038/nature12638. Epub 2013 Oct 20. Nature. 2013. PMID: 24141947 Free PMC article.
LUBAC synthesizes linear ubiquitin chains via a thioester intermediate.
Stieglitz B, Morris-Davies AC, Koliopoulos MG, Christodoulou E, Rittinger K. Stieglitz B, et al. Among authors: christodoulou e. EMBO Rep. 2012 Sep;13(9):840-6. doi: 10.1038/embor.2012.105. Epub 2012 Jul 13. EMBO Rep. 2012. PMID: 22791023 Free PMC article.
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase.
Goldstone DC, Ennis-Adeniran V, Hedden JJ, Groom HC, Rice GI, Christodoulou E, Walker PA, Kelly G, Haire LF, Yap MW, de Carvalho LP, Stoye JP, Crow YJ, Taylor IA, Webb M. Goldstone DC, et al. Among authors: christodoulou e. Nature. 2011 Nov 6;480(7377):379-82. doi: 10.1038/nature10623. Nature. 2011. PMID: 22056990
Structural basis of substrate discrimination and integrin binding by autotaxin.
Hausmann J, Kamtekar S, Christodoulou E, Day JE, Wu T, Fulkerson Z, Albers HM, van Meeteren LA, Houben AJ, van Zeijl L, Jansen S, Andries M, Hall T, Pegg LE, Benson TE, Kasiem M, Harlos K, Kooi CW, Smyth SS, Ovaa H, Bollen M, Morris AJ, Moolenaar WH, Perrakis A. Hausmann J, et al. Among authors: christodoulou e. Nat Struct Mol Biol. 2011 Feb;18(2):198-204. doi: 10.1038/nsmb.1980. Epub 2011 Jan 16. Nat Struct Mol Biol. 2011. PMID: 21240271 Free PMC article.
Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development.
Green JL, Wu Y, Encheva V, Lasonder E, Prommaban A, Kunzelmann S, Christodoulou E, Grainger M, Truongvan N, Bothe S, Sharma V, Song W, Pinzuti I, Uthaipibull C, Srichairatanakool S, Birault V, Langsley G, Schindelin H, Stieglitz B, Snijders AP, Holder AA. Green JL, et al. Among authors: christodoulou e. PLoS Pathog. 2020 Jun 22;16(6):e1008640. doi: 10.1371/journal.ppat.1008640. eCollection 2020 Jun. PLoS Pathog. 2020. PMID: 32569299 Free PMC article.
203 results