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Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
Morgenstern M, Peikert CD, Lübbert P, Suppanz I, Klemm C, Alka O, Steiert C, Naumenko N, Schendzielorz A, Melchionda L, Mühlhäuser WWD, Knapp B, Busch JD, Stiller SB, Dannenmaier S, Lindau C, Licheva M, Eickhorst C, Galbusera R, Zerbes RM, Ryan MT, Kraft C, Kozjak-Pavlovic V, Drepper F, Dennerlein S, Oeljeklaus S, Pfanner N, Wiedemann N, Warscheid B. Morgenstern M, et al. Among authors: eickhorst c. Cell Metab. 2021 Dec 7;33(12):2464-2483.e18. doi: 10.1016/j.cmet.2021.11.001. Epub 2021 Nov 19. Cell Metab. 2021. PMID: 34800366 Free PMC article.
FIP200 Phosphorylation Regulates Late Steps in Mitophagy.
Eickhorst C, Babic R, Rush-Kittle J, Lucya L, Imam FL, Sánchez-Martín P, Hollenstein DM, Michaelis J, Münch C, Meisinger C, Slade D, Gámez-Díaz L, Kraft C. Eickhorst C, et al. J Mol Biol. 2024 Aug 1;436(15):168631. doi: 10.1016/j.jmb.2024.168631. Epub 2024 May 29. J Mol Biol. 2024. PMID: 38821350 Free article.
Scaffold proteins in bulk and selective autophagy.
Eickhorst C, Licheva M, Kraft C. Eickhorst C, et al. Prog Mol Biol Transl Sci. 2020;172:15-35. doi: 10.1016/bs.pmbts.2020.01.009. Epub 2020 Mar 6. Prog Mol Biol Transl Sci. 2020. PMID: 32620241 Review.
Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy.
Licheva M, Pflaum J, Babic R, Mancilla H, Elsässer J, Boyle E, Hollenstein DM, Jimenez-Niebla J, Pleyer J, Heinrich M, Wieland FG, Brenneisen J, Eickhorst C, Brenner J, Jiang S, Hartl M, Welsch S, Hunte C, Timmer J, Wilfling F, Kraft C. Licheva M, et al. Among authors: eickhorst c. Nat Cell Biol. 2025 Feb;27(2):283-297. doi: 10.1038/s41556-024-01572-y. Epub 2025 Jan 7. Nat Cell Biol. 2025. PMID: 39774270 Free PMC article.
mTOR controls embryonic and adult myogenesis via mTORC1.
Rion N, Castets P, Lin S, Enderle L, Reinhard JR, Eickhorst C, Rüegg MA. Rion N, et al. Among authors: eickhorst c. Development. 2019 Apr 8;146(7):dev172460. doi: 10.1242/dev.172460. Development. 2019. PMID: 30872276