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I86A/C295A mutant secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus has broadened substrate specificity for aryl ketones.
Arch Biochem Biophys. 2016 Sep 15;606:151-6. doi: 10.1016/j.abb.2016.08.002. Epub 2016 Aug 3.
Arch Biochem Biophys. 2016.
PMID: 27495738
Mutagenesis of Met-151 and Thr-153 to alanine in Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase changes substrate specificity for acetophenones.
Nealon CM, Kim CS, Dwamena AK, Phillips RS.
Nealon CM, et al.
Enzyme Microb Technol. 2017 Oct;105:59-63. doi: 10.1016/j.enzmictec.2017.06.010. Epub 2017 Jun 23.
Enzyme Microb Technol. 2017.
PMID: 28756862
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