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Deconvoluting the Molecular Control of Binding and Signaling at the Amylin 3 Receptor: RAMP3 Alters Signal Propagation through Extracellular Loops of the Calcitonin Receptor.
Pham V, Zhu Y, Dal Maso E, Reynolds CA, Deganutti G, Atanasio S, Hick CA, Yang D, Christopoulos A, Hay DL, Furness SGB, Wang MW, Wootten D, Sexton PM. Pham V, et al. Among authors: christopoulos a. ACS Pharmacol Transl Sci. 2019 Mar 18;2(3):183-197. doi: 10.1021/acsptsci.9b00010. eCollection 2019 Jun 14. ACS Pharmacol Transl Sci. 2019. PMID: 32219220 Free PMC article.
Novel receptor partners and function of receptor activity-modifying proteins.
Christopoulos A, Christopoulos G, Morfis M, Udawela M, Laburthe M, Couvineau A, Kuwasako K, Tilakaratne N, Sexton PM. Christopoulos A, et al. Among authors: christopoulos g. J Biol Chem. 2003 Jan 31;278(5):3293-7. doi: 10.1074/jbc.C200629200. Epub 2002 Nov 21. J Biol Chem. 2003. PMID: 12446722 Free article.
RAMPs: 5 years on, where to now?
Morfis M, Christopoulos A, Sexton PM. Morfis M, et al. Among authors: christopoulos a. Trends Pharmacol Sci. 2003 Nov;24(11):596-601. doi: 10.1016/j.tips.2003.09.001. Trends Pharmacol Sci. 2003. PMID: 14607083 Review.
Allosteric modulation of G protein-coupled receptors.
May LT, Avlani VA, Sexton PM, Christopoulos A. May LT, et al. Among authors: christopoulos a. Curr Pharm Des. 2004;10(17):2003-13. doi: 10.2174/1381612043384303. Curr Pharm Des. 2004. PMID: 15279541 Review.
Amylin receptors: molecular composition and pharmacology.
Hay DL, Christopoulos G, Christopoulos A, Sexton PM. Hay DL, et al. Among authors: christopoulos a, christopoulos g. Biochem Soc Trans. 2004 Nov;32(Pt 5):865-7. doi: 10.1042/BST0320865. Biochem Soc Trans. 2004. PMID: 15494035 Review.
432 results