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The JNK inhibitor XG-102 protects against TNBS-induced colitis.
Reinecke K, Eminel S, Dierck F, Roessner W, Kersting S, Chromik AM, Gavrilova O, Laukevicience A, Leuschner I, Waetzig V, Rosenstiel P, Herdegen T, Sina C. Reinecke K, et al. Among authors: chromik am. PLoS One. 2012;7(3):e30985. doi: 10.1371/journal.pone.0030985. Epub 2012 Mar 13. PLoS One. 2012. PMID: 22427801 Free PMC article.
Specific pathophysiological functions of JNK isoforms in the brain.
Brecht S, Kirchhof R, Chromik A, Willesen M, Nicolaus T, Raivich G, Wessig J, Waetzig V, Goetz M, Claussen M, Pearse D, Kuan CY, Vaudano E, Behrens A, Wagner E, Flavell RA, Davis RJ, Herdegen T. Brecht S, et al. Eur J Neurosci. 2005 Jan;21(2):363-77. doi: 10.1111/j.1460-9568.2005.03857.x. Eur J Neurosci. 2005. PMID: 15673436
Knockout of the c-Jun N-terminal Kinase 2 aggravates the development of mild chronic dextran sulfate sodium colitis independently of expression of intestinal cytokines TNFα, TGFB1, and IL-6.
Kersting S, Reinecke K, Hilgert C, Janot MS, Haarmann E, Albrecht M, Müller AM, Herdegen T, Mittelkötter U, Uhl W, Chromik AM. Kersting S, et al. Among authors: chromik am. J Inflamm Res. 2013;6:13-23. doi: 10.2147/JIR.S36415. Epub 2013 Feb 12. J Inflamm Res. 2013. PMID: 23426157 Free PMC article.
67 results