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Chronic pharyngeal carriage of group A streptococci.
Tanz RR, Shulman ST. Tanz RR, et al. Pediatr Infect Dis J. 2007 Feb;26(2):175-6. doi: 10.1097/01.inf.0000255328.19808.be. Pediatr Infect Dis J. 2007. PMID: 17259882 Review. No abstract available.
Clindamycin treatment of chronic pharyngeal carriage of group A streptococci.
Tanz RR, Poncher JR, Corydon KE, Kabat K, Yogev R, Shulman ST. Tanz RR, et al. J Pediatr. 1991 Jul;119(1 Pt 1):123-8. doi: 10.1016/s0022-3476(05)81052-2. J Pediatr. 1991. PMID: 2066844 Clinical Trial.
We previously demonstrated that chronic pharyngeal carriage of group A beta-hemolytic streptococci (GABHS) can be terminated by intramuscular administration of benzathine penicillin plus 4 days of orally administered rifampin. ...Treatment success was defined …
We previously demonstrated that chronic pharyngeal carriage of group A beta-hemolytic streptococci (GABHS) can be termi …
Management of children with persistent group A streptococcal carriage.
Zacharioudaki ME, Galanakis E. Zacharioudaki ME, et al. Expert Rev Anti Infect Ther. 2017 Aug;15(8):787-795. doi: 10.1080/14787210.2017.1358612. Epub 2017 Jul 31. Expert Rev Anti Infect Ther. 2017. PMID: 28730858 Review.
Chronic GAS carrier state is best defined as the prolonged presence of group A beta-haemolytic Streptococcus (GAS) in the pharynx without evidence of infection or inflammation. Chronic GAS carriers have a low risk of immune mediated complications. Pers
Chronic GAS carrier state is best defined as the prolonged presence of group A beta-haemolytic Streptococcus (GAS) in the p
Detection of group A Streptococcus in tonsils from pediatric patients reveals high rate of asymptomatic streptococcal carriage.
Roberts AL, Connolly KL, Kirse DJ, Evans AK, Poehling KA, Peters TR, Reid SD. Roberts AL, et al. BMC Pediatr. 2012 Jan 9;12:3. doi: 10.1186/1471-2431-12-3. BMC Pediatr. 2012. PMID: 22230361 Free PMC article.
BACKGROUND: Group A Streptococcus (GAS) causes acute tonsillopharyngitis in children, and approximately 20% of this population are chronic carriers of GAS. Antibacterial therapy has previously been shown to be insufficient at clearing GAS carriage. Bacterial …
BACKGROUND: Group A Streptococcus (GAS) causes acute tonsillopharyngitis in children, and approximately 20% of this population are …
Penicillin plus rifampin eradicates pharyngeal carriage of group A streptococci.
Tanz RR, Shulman ST, Barthel MJ, Willert C, Yogev R. Tanz RR, et al. J Pediatr. 1985 Jun;106(6):876-80. doi: 10.1016/s0022-3476(85)80229-8. J Pediatr. 1985. PMID: 3889257 Clinical Trial.
We evaluated the efficacy of rifampin in eradicating chronic pharyngeal carriage of group A streptococci. Carriers were defined as healthy children whose throat cultures showed persistence of group A streptococci 3 weeks after receiving benzathine penicillin …
We evaluated the efficacy of rifampin in eradicating chronic pharyngeal carriage of group A streptococci. Carriers were …
Asymptomatic Group A Streptococcus carriage in children with recurrent tonsillitis and tonsillar hypertrophy.
Pontin IP, Sanchez DC, Di Francesco R. Pontin IP, et al. Int J Pediatr Otorhinolaryngol. 2016 Jul;86:57-9. doi: 10.1016/j.ijporl.2016.03.044. Epub 2016 Apr 12. Int J Pediatr Otorhinolaryngol. 2016. PMID: 27260580
BACKGROUND: Group A Streptococcus (GAS) is the most important bacterial cause of acute tonsillitis in children. Some children are chronic GAS carriers, and this carriage is poorly understood. We determined the frequency of GAS detection using a rapid antigen …
BACKGROUND: Group A Streptococcus (GAS) is the most important bacterial cause of acute tonsillitis in children. Some children are …
An Experimental Group A Streptococcus Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model.
Rivera-Hernandez T, Carnathan DG, Jones S, Cork AJ, Davies MR, Moyle PM, Toth I, Batzloff MR, McCarthy J, Nizet V, Goldblatt D, Silvestri G, Walker MJ. Rivera-Hernandez T, et al. mBio. 2019 Apr 30;10(2):e00693-19. doi: 10.1128/mBio.00693-19. mBio. 2019. PMID: 31040243 Free PMC article.
Group A Streptococcus (GAS) infections account for an estimated 500,000 deaths every year. This bacterial pathogen is responsible for a variety of mild and life-threatening infections and the triggering of chronic autoimmune sequelae. Pharyngitis caused by group A …
Group A Streptococcus (GAS) infections account for an estimated 500,000 deaths every year. This bacterial pathogen is responsible for …
Streptolysin O and its co-toxin NAD-glycohydrolase protect group A Streptococcus from Xenophagic killing.
O'Seaghdha M, Wessels MR. O'Seaghdha M, et al. PLoS Pathog. 2013;9(6):e1003394. doi: 10.1371/journal.ppat.1003394. Epub 2013 Jun 6. PLoS Pathog. 2013. PMID: 23762025 Free PMC article.
Group A Streptococcus (Streptococcus pyogenes or GAS) causes pharyngitis, severe invasive infections, and the post-infectious syndromes of glomerulonephritis and rheumatic fever. ...This novel activity of NADase to block autophagic killing of GAS in pharyn
Group A Streptococcus (Streptococcus pyogenes or GAS) causes pharyngitis, severe invasive infections, and the post-infe …
Evaluation of new anti-infective drugs for the treatment of respiratory tract infections. Infectious Diseases Society of America and the Food and Drug Administration.
Chow AW, Hall CB, Klein JO, Kammer RB, Meyer RD, Remington JS. Chow AW, et al. Clin Infect Dis. 1992 Nov;15 Suppl 1(Suppl 1):S62-88. doi: 10.1093/clind/15.supplement_1.s62. Clin Infect Dis. 1992. PMID: 1477253 Free PMC article.
Establishment of the microbial etiology of respiratory tract infections is hampered by the presence of "normal flora" of the nose, mouth, and pharynx, which may include asymptomatic carriage of potential pathogens. This issue is addressed for each category of infect …
Establishment of the microbial etiology of respiratory tract infections is hampered by the presence of "normal flora" of the nose, mouth, an …
Selected bacterial recovery in Trinidadian children with chronic tonsillar disease.
Pereira LMP, Juman S, Bekele I, Seepersadsingh N, Adesiyun AA. Pereira LMP, et al. Braz J Otorhinolaryngol. 2008 Nov-Dec;74(6):903-911. doi: 10.1016/S1808-8694(15)30152-X. Braz J Otorhinolaryngol. 2008. PMID: 19582348 Free PMC article.
More (p<0.001) surfaces (82.2%) than cores (63.3%) grew Streptococcus spp.; alpha-haemolytic Streptococcus prevalence was higher (p<0.001) than ss-haemolytic Streptococcus on surfaces (74.4% vs. 18.6%) than cores (58.9% vs. 13.7%). ...CONCLUSION: Tonsil …
More (p<0.001) surfaces (82.2%) than cores (63.3%) grew Streptococcus spp.; alpha-haemolytic Streptococcus prevalence was h …