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Human glucocorticoid receptor isoform beta: recent understanding of its potential implications in physiology and pathophysiology.
Kino T, Su YA, Chrousos GP. Kino T, et al. Cell Mol Life Sci. 2009 Nov;66(21):3435-48. doi: 10.1007/s00018-009-0098-z. Epub 2009 Jul 26. Cell Mol Life Sci. 2009. PMID: 19633971 Free PMC article. Review.
Nuclear receptor coactivator p160 proteins enhance the HIV-1 long terminal repeat promoter by bridging promoter-bound factors and the Tat-P-TEFb complex.
Kino T, Slobodskaya O, Pavlakis GN, Chrousos GP. Kino T, et al. J Biol Chem. 2002 Jan 25;277(4):2396-405. doi: 10.1074/jbc.M106312200. Epub 2001 Nov 9. J Biol Chem. 2002. PMID: 11704662
Positive effects of glucocorticoids on T cell function by up-regulation of IL-7 receptor alpha.
Franchimont D, Galon J, Vacchio MS, Fan S, Visconti R, Frucht DM, Geenen V, Chrousos GP, Ashwell JD, O'Shea JJ. Franchimont D, et al. J Immunol. 2002 Mar 1;168(5):2212-8. doi: 10.4049/jimmunol.168.5.2212. J Immunol. 2002. PMID: 11859107
A novel, C-terminal dominant negative mutation of the GR causes familial glucocorticoid resistance through abnormal interactions with p160 steroid receptor coactivators.
Vottero A, Kino T, Combe H, Lecomte P, Chrousos GP. Vottero A, et al. J Clin Endocrinol Metab. 2002 Jun;87(6):2658-67. doi: 10.1210/jcem.87.6.8520. J Clin Endocrinol Metab. 2002. PMID: 12050230
Increased glucocorticoid receptor Beta expression converts mouse hybridoma cells to a corticosteroid-insensitive phenotype.
Hauk PJ, Goleva E, Strickland I, Vottero A, Chrousos GP, Kisich KO, Leung DY. Hauk PJ, et al. Am J Respir Cell Mol Biol. 2002 Sep;27(3):361-7. doi: 10.1165/rcmb.4861. Am J Respir Cell Mol Biol. 2002. PMID: 12204899
Human immunodeficiency virus type 1 (HIV-1) accessory protein Vpr induces transcription of the HIV-1 and glucocorticoid-responsive promoters by binding directly to p300/CBP coactivators.
Kino T, Gragerov A, Slobodskaya O, Tsopanomichalou M, Chrousos GP, Pavlakis GN. Kino T, et al. J Virol. 2002 Oct;76(19):9724-34. doi: 10.1128/jvi.76.19.9724-9734.2002. J Virol. 2002. PMID: 12208951 Free PMC article.
Transcription factor TFIIH components enhance the GR coactivator activity but not the cell cycle-arresting activity of the human immunodeficiency virus type-1 protein Vpr.
Kino T, Tsukamoto M, Chrousos G. Kino T, et al. Biochem Biophys Res Commun. 2002 Oct 18;298(1):17-23. doi: 10.1016/s0006-291x(02)02442-7. Biochem Biophys Res Commun. 2002. PMID: 12379213
Familial/sporadic glucocorticoid resistance syndrome and hypertension.
Kino T, Vottero A, Charmandari E, Chrousos GP. Kino T, et al. Ann N Y Acad Sci. 2002 Sep;970:101-11. doi: 10.1111/j.1749-6632.2002.tb04416.x. Ann N Y Acad Sci. 2002. PMID: 12381545 Review.
HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection.
Mirani M, Elenkov I, Volpi S, Hiroi N, Chrousos GP, Kino T. Mirani M, et al. J Immunol. 2002 Dec 1;169(11):6361-8. doi: 10.4049/jimmunol.169.11.6361. J Immunol. 2002. PMID: 12444143
Tumor necrosis factor alpha receptor- and Fas-associated FLASH inhibit transcriptional activity of the glucocorticoid receptor by binding to and interfering with its interaction with p160 type nuclear receptor coactivators.
Kino T, Chrousos GP. Kino T, et al. J Biol Chem. 2003 Jan 31;278(5):3023-9. doi: 10.1074/jbc.M209234200. Epub 2002 Dec 10. J Biol Chem. 2003. PMID: 12477726
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