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Focal adhesions, contractility, and signaling.
Burridge K, Chrzanowska-Wodnicka M. Burridge K, et al. Annu Rev Cell Dev Biol. 1996;12:463-518. doi: 10.1146/annurev.cellbio.12.1.463. Annu Rev Cell Dev Biol. 1996. PMID: 8970735 Review.
Rap1b is critical for glycoprotein VI-mediated but not ADP receptor-mediated alpha2beta1 activation.
Wang Z, Holly SP, Larson MK, Liu J, Yuan W, Chrzanowska-Wodnicka M, White GC 2nd, Parise LV. Wang Z, et al. J Thromb Haemost. 2009 Apr;7(4):693-700. doi: 10.1111/j.1538-7836.2009.03289.x. Epub 2009 Jan 17. J Thromb Haemost. 2009. PMID: 19192113 Free PMC article.
G2A is an oncogenic G protein-coupled receptor.
Zohn IE, Klinger M, Karp X, Kirk H, Symons M, Chrzanowska-Wodnicka M, Der CJ, Kay RJ. Zohn IE, et al. Oncogene. 2000 Aug 10;19(34):3866-77. doi: 10.1038/sj.onc.1203731. Oncogene. 2000. PMID: 10951580
Microtubule depolymerization induces stress fibers, focal adhesions, and DNA synthesis via the GTP-binding protein Rho.
Liu BP, Chrzanowska-Wodnicka M, Burridge K. Liu BP, et al. Cell Adhes Commun. 1998 Jun;5(4):249-55. doi: 10.3109/15419069809040295. Cell Adhes Commun. 1998. PMID: 9762466
Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly.
Zhong C, Chrzanowska-Wodnicka M, Brown J, Shaub A, Belkin AM, Burridge K. Zhong C, et al. J Cell Biol. 1998 Apr 20;141(2):539-51. doi: 10.1083/jcb.141.2.539. J Cell Biol. 1998. PMID: 9548730 Free PMC article.
Mas oncogene signaling and transformation require the small GTP-binding protein Rac.
Zohn IE, Symons M, Chrzanowska-Wodnicka M, Westwick JK, Der CJ. Zohn IE, et al. Mol Cell Biol. 1998 Mar;18(3):1225-35. doi: 10.1128/mcb.18.3.1225. Mol Cell Biol. 1998. PMID: 9488437 Free PMC article.
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.
Chrzanowska-Wodnicka M, Burridge K. Chrzanowska-Wodnicka M, et al. J Cell Biol. 1996 Jun;133(6):1403-15. doi: 10.1083/jcb.133.6.1403. J Cell Biol. 1996. PMID: 8682874 Free PMC article.
Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation.
Khosravi-Far R, White MA, Westwick JK, Solski PA, Chrzanowska-Wodnicka M, Van Aelst L, Wigler MH, Der CJ. Khosravi-Far R, et al. Mol Cell Biol. 1996 Jul;16(7):3923-33. doi: 10.1128/mcb.16.7.3923. Mol Cell Biol. 1996. PMID: 8668210 Free PMC article.
Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras.
Khosravi-Far R, Chrzanowska-Wodnicka M, Solski PA, Eva A, Burridge K, Der CJ. Khosravi-Far R, et al. Mol Cell Biol. 1994 Oct;14(10):6848-57. doi: 10.1128/mcb.14.10.6848. Mol Cell Biol. 1994. PMID: 7935402 Free PMC article.
Rho, rac and the actin cytoskeleton.
Chrzanowska-Wodnicka M, Burridge K. Chrzanowska-Wodnicka M, et al. Bioessays. 1992 Nov;14(11):777-8. doi: 10.1002/bies.950141110. Bioessays. 1992. PMID: 1365891 Review. No abstract available.
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