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194 results
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Transcriptional networks: reverse-engineering gene regulation on a global scale.
Chua G, Robinson MD, Morris Q, Hughes TR. Chua G, et al. Curr Opin Microbiol. 2004 Dec;7(6):638-46. doi: 10.1016/j.mib.2004.10.009. Curr Opin Microbiol. 2004. PMID: 15556037 Review.
Mapping pathways and phenotypes by systematic gene overexpression.
Sopko R, Huang D, Preston N, Chua G, Papp B, Kafadar K, Snyder M, Oliver SG, Cyert M, Hughes TR, Boone C, Andrews B. Sopko R, et al. Among authors: chua g. Mol Cell. 2006 Feb 3;21(3):319-30. doi: 10.1016/j.molcel.2005.12.011. Mol Cell. 2006. PMID: 16455487
Using expression profiling data to identify human microRNA targets.
Huang JC, Babak T, Corson TW, Chua G, Khan S, Gallie BL, Hughes TR, Blencowe BJ, Frey BJ, Morris QD. Huang JC, et al. Among authors: chua g. Nat Methods. 2007 Dec;4(12):1045-9. doi: 10.1038/nmeth1130. Epub 2007 Nov 18. Nat Methods. 2007. PMID: 18026111
Conservation of core gene expression in vertebrate tissues.
Chan ET, Quon GT, Chua G, Babak T, Trochesset M, Zirngibl RA, Aubin J, Ratcliffe MJ, Wilde A, Brudno M, Morris QD, Hughes TR. Chan ET, et al. Among authors: chua g. J Biol. 2009;8(3):33. doi: 10.1186/jbiol130. Epub 2009 Apr 16. J Biol. 2009. PMID: 19371447 Free PMC article.
Comprehensive genetic analysis of transcription factor pathways using a dual reporter gene system in budding yeast.
Kainth P, Sassi HE, Peña-Castillo L, Chua G, Hughes TR, Andrews B. Kainth P, et al. Among authors: chua g. Methods. 2009 Jul;48(3):258-64. doi: 10.1016/j.ymeth.2009.02.015. Epub 2009 Mar 6. Methods. 2009. PMID: 19269327
Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes.
Dixon SJ, Fedyshyn Y, Koh JL, Prasad TS, Chahwan C, Chua G, Toufighi K, Baryshnikova A, Hayles J, Hoe KL, Kim DU, Park HO, Myers CL, Pandey A, Durocher D, Andrews BJ, Boone C. Dixon SJ, et al. Among authors: chua g. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16653-8. doi: 10.1073/pnas.0806261105. Epub 2008 Oct 17. Proc Natl Acad Sci U S A. 2008. PMID: 18931302 Free PMC article.
Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast.
Parsons AB, Lopez A, Givoni IE, Williams DE, Gray CA, Porter J, Chua G, Sopko R, Brost RL, Ho CH, Wang J, Ketela T, Brenner C, Brill JA, Fernandez GE, Lorenz TC, Payne GS, Ishihara S, Ohya Y, Andrews B, Hughes TR, Frey BJ, Graham TR, Andersen RJ, Boone C. Parsons AB, et al. Among authors: chua g. Cell. 2006 Aug 11;126(3):611-25. doi: 10.1016/j.cell.2006.06.040. Cell. 2006. PMID: 16901791
Identifying transcription factor functions and targets by phenotypic activation.
Chua G, Morris QD, Sopko R, Robinson MD, Ryan O, Chan ET, Frey BJ, Andrews BJ, Boone C, Hughes TR. Chua G, et al. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12045-50. doi: 10.1073/pnas.0605140103. Epub 2006 Jul 31. Proc Natl Acad Sci U S A. 2006. PMID: 16880382 Free PMC article.
Global mapping of the yeast genetic interaction network.
Tong AH, Lesage G, Bader GD, Ding H, Xu H, Xin X, Young J, Berriz GF, Brost RL, Chang M, Chen Y, Cheng X, Chua G, Friesen H, Goldberg DS, Haynes J, Humphries C, He G, Hussein S, Ke L, Krogan N, Li Z, Levinson JN, Lu H, Ménard P, Munyana C, Parsons AB, Ryan O, Tonikian R, Roberts T, Sdicu AM, Shapiro J, Sheikh B, Suter B, Wong SL, Zhang LV, Zhu H, Burd CG, Munro S, Sander C, Rine J, Greenblatt J, Peter M, Bretscher A, Bell G, Roth FP, Brown GW, Andrews B, Bussey H, Boone C. Tong AH, et al. Among authors: chua g. Science. 2004 Feb 6;303(5659):808-13. doi: 10.1126/science.1091317. Science. 2004. PMID: 14764870
Exploration of essential gene functions via titratable promoter alleles.
Mnaimneh S, Davierwala AP, Haynes J, Moffat J, Peng WT, Zhang W, Yang X, Pootoolal J, Chua G, Lopez A, Trochesset M, Morse D, Krogan NJ, Hiley SL, Li Z, Morris Q, Grigull J, Mitsakakis N, Roberts CJ, Greenblatt JF, Boone C, Kaiser CA, Andrews BJ, Hughes TR. Mnaimneh S, et al. Among authors: chua g. Cell. 2004 Jul 9;118(1):31-44. doi: 10.1016/j.cell.2004.06.013. Cell. 2004. PMID: 15242642
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