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Long term management of patients with cryopyrin-associated periodic syndromes (CAPS): focus on rilonacept (IL-1 Trap).
Church LD, Savic S, McDermott MF. Church LD, et al. Biologics. 2008 Dec;2(4):733-42. doi: 10.2147/btt.s3167. Biologics. 2008. PMID: 19707454 Free PMC article.
Rilonacept in cryopyrin-associated periodic syndromes: the beginning of longer-acting interleukin-1 antagonism.
Church LD, McDermott MF. Church LD, et al. Nat Clin Pract Rheumatol. 2009 Jan;5(1):14-5. doi: 10.1038/ncprheum0959. Epub 2008 Nov 18. Nat Clin Pract Rheumatol. 2009. PMID: 19015646 No abstract available.
Canakinumab: a human anti-IL-1β monoclonal antibody for the treatment of cryopyrin-associated periodic syndromes.
Church LD, McDermott MF. Church LD, et al. Expert Rev Clin Immunol. 2010 Nov;6(6):831-41. doi: 10.1586/eci.10.66. Expert Rev Clin Immunol. 2010. PMID: 20979548
Rheumatoid synovial fluid interleukin-17-producing CD4 T cells have abundant tumor necrosis factor-alpha co-expression, but little interleukin-22 and interleukin-23R expression.
Church LD, Filer AD, Hidalgo E, Howlett KA, Thomas AM, Rapecki S, Scheel-Toellner D, Buckley CD, Raza K. Church LD, et al. Arthritis Res Ther. 2010;12(5):R184. doi: 10.1186/ar3152. Epub 2010 Oct 7. Arthritis Res Ther. 2010. PMID: 20929536 Free PMC article.
Primer: inflammasomes and interleukin 1beta in inflammatory disorders.
Church LD, Cook GP, McDermott MF. Church LD, et al. Nat Clin Pract Rheumatol. 2008 Jan;4(1):34-42. doi: 10.1038/ncprheum0681. Nat Clin Pract Rheumatol. 2008. PMID: 18172447 Review.
Linking power Doppler ultrasound to the presence of th17 cells in the rheumatoid arthritis joint.
Gullick NJ, Evans HG, Church LD, Jayaraj DM, Filer A, Kirkham BW, Taams LS. Gullick NJ, et al. Among authors: church ld. PLoS One. 2010 Sep 1;5(9):e12516. doi: 10.1371/journal.pone.0012516. PLoS One. 2010. PMID: 20824142 Free PMC article.
Intracellular calcium signalling patterns reflect the differentiation status of human T cells.
Arrol HP, Church LD, Bacon PA, Young SP. Arrol HP, et al. Among authors: church ld. Clin Exp Immunol. 2008 Jul;153(1):86-95. doi: 10.1111/j.1365-2249.2008.03677.x. Epub 2008 May 5. Clin Exp Immunol. 2008. PMID: 18460013 Free PMC article.
TNFR1-induced sphingomyelinase activation modulates TCR signaling by impairing store-operated Ca2+ influx.
Church LD, Hessler G, Goodall JE, Rider DA, Workman CJ, Vignali DA, Bacon PA, Gulbins E, Young SP. Church LD, et al. J Leukoc Biol. 2005 Jul;78(1):266-78. doi: 10.1189/jlb.1003456. Epub 2005 Apr 7. J Leukoc Biol. 2005. PMID: 15817701
Proinflammatory action of the antiinflammatory drug infliximab in tumor necrosis factor receptor-associated periodic syndrome.
Nedjai B, Hitman GA, Quillinan N, Coughlan RJ, Church L, McDermott MF, Turner MD. Nedjai B, et al. Among authors: church l. Arthritis Rheum. 2009 Feb;60(2):619-25. doi: 10.1002/art.24294. Arthritis Rheum. 2009. PMID: 19180495
Vitamin D3 down-regulates intracellular Toll-like receptor 9 expression and Toll-like receptor 9-induced IL-6 production in human monocytes.
Dickie LJ, Church LD, Coulthard LR, Mathews RJ, Emery P, McDermott MF. Dickie LJ, et al. Among authors: church ld. Rheumatology (Oxford). 2010 Aug;49(8):1466-71. doi: 10.1093/rheumatology/keq124. Epub 2010 Apr 30. Rheumatology (Oxford). 2010. PMID: 20435648
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