Chytil A - Search Results

1

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma.

Ijichi H, Chytil A, Gorska AE, Aakre ME, Bierie B, Tada M, Mohri D, Miyabayashi K, Asaoka Y, Maeda S, Ikenoue T, Tateishi K, Wright CV, Koike K, Omata M, Moses HL. Ijichi H, et al. Among authors: chytil a. J Clin Invest. 2011 Oct;121(10):4106-17. doi: 10.1172/JCI42754. Epub 2011 Sep 19. J Clin Invest. 2011. PMID: 21926469 Free PMC article.

2

Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer.

Bierie B, Chung CH, Parker JS, Stover DG, Cheng N, Chytil A, Aakre M, Shyr Y, Moses HL. Bierie B, et al. Among authors: chytil a. J Clin Invest. 2009 Jun;119(6):1571-82. doi: 10.1172/JCI37480. Epub 2009 May 18. J Clin Invest. 2009. PMID: 19451693 Free PMC article.

3

Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression.

Ijichi H, Chytil A, Gorska AE, Aakre ME, Fujitani Y, Fujitani S, Wright CV, Moses HL. Ijichi H, et al. Among authors: chytil a. Genes Dev. 2006 Nov 15;20(22):3147-60. doi: 10.1101/gad.1475506. Genes Dev. 2006. PMID: 17114585 Free PMC article.

4

Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment.

Bierie B, Stover DG, Abel TW, Chytil A, Gorska AE, Aakre M, Forrester E, Yang L, Wagner KU, Moses HL. Bierie B, et al. Among authors: chytil a. Cancer Res. 2008 Mar 15;68(6):1809-19. doi: 10.1158/0008-5472.CAN-07-5597. Cancer Res. 2008. PMID: 18339861

5

Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis.

Forrester E, Chytil A, Bierie B, Aakre M, Gorska AE, Sharif-Afshar AR, Muller WJ, Moses HL. Forrester E, et al. Among authors: chytil a. Cancer Res. 2005 Mar 15;65(6):2296-302. doi: 10.1158/0008-5472.CAN-04-3272. Cancer Res. 2005. PMID: 15781643

6

Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.

Biswas S, Guix M, Rinehart C, Dugger TC, Chytil A, Moses HL, Freeman ML, Arteaga CL. Biswas S, et al. Among authors: chytil a. J Clin Invest. 2007 May;117(5):1305-13. doi: 10.1172/JCI30740. Epub 2007 Apr 5. J Clin Invest. 2007. PMID: 17415413 Free PMC article.

7

Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis.

Yang L, Huang J, Ren X, Gorska AE, Chytil A, Aakre M, Carbone DP, Matrisian LM, Richmond A, Lin PC, Moses HL. Yang L, et al. Among authors: chytil a. Cancer Cell. 2008 Jan;13(1):23-35. doi: 10.1016/j.ccr.2007.12.004. Cancer Cell. 2008. PMID: 18167337 Free PMC article.

8

Loss of one Tgfbr2 allele in fibroblasts promotes metastasis in MMTV: polyoma middle T transgenic and transplant mouse models of mammary tumor progression.

Fang WB, Jokar I, Chytil A, Moses HL, Abel T, Cheng N. Fang WB, et al. Among authors: chytil a. Clin Exp Metastasis. 2011 Apr;28(4):351-66. doi: 10.1007/s10585-011-9373-0. Epub 2011 Mar 4. Clin Exp Metastasis. 2011. PMID: 21374085 Free PMC article.

9

Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators.

Owens P, Pickup MW, Novitskiy SV, Chytil A, Gorska AE, Aakre ME, West J, Moses HL. Owens P, et al. Among authors: chytil a. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2814-9. doi: 10.1073/pnas.1101139108. Epub 2011 May 16. Proc Natl Acad Sci U S A. 2012. PMID: 21576484 Free PMC article.

10

TGF-β receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanisms.

Novitskiy SV, Pickup MW, Gorska AE, Owens P, Chytil A, Aakre M, Wu H, Shyr Y, Moses HL. Novitskiy SV, et al. Among authors: chytil a. Cancer Discov. 2011 Oct;1(5):430-41. doi: 10.1158/2159-8290.CD-11-0100. Cancer Discov. 2011. PMID: 22408746 Free PMC article.

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