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The ubiquitin system for protein degradation.
Hershko A, Ciechanover A. Hershko A, et al. Among authors: ciechanover a. Annu Rev Biochem. 1992;61:761-807. doi: 10.1146/annurev.bi.61.070192.003553. Annu Rev Biochem. 1992. PMID: 1323239 Review. No abstract available.
Degradation of nuclear oncoproteins by the ubiquitin system in vitro.
Ciechanover A, DiGiuseppe JA, Bercovich B, Orian A, Richter JD, Schwartz AL, Brodeur GM. Ciechanover A, et al. Proc Natl Acad Sci U S A. 1991 Jan 1;88(1):139-43. doi: 10.1073/pnas.88.1.139. Proc Natl Acad Sci U S A. 1991. PMID: 1846034 Free PMC article.
Mechanisms of intracellular protein breakdown.
Hershko A, Ciechanover A. Hershko A, et al. Among authors: ciechanover a. Annu Rev Biochem. 1982;51:335-64. doi: 10.1146/annurev.bi.51.070182.002003. Annu Rev Biochem. 1982. PMID: 6287917 Review. No abstract available.
Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation.
Orian A, Whiteside S, Israël A, Stancovski I, Schwartz AL, Ciechanover A. Orian A, et al. Among authors: ciechanover a. J Biol Chem. 1995 Sep 15;270(37):21707-14. doi: 10.1074/jbc.270.37.21707. J Biol Chem. 1995. PMID: 7665588
Purification, characterization, and rapid inactivation of thermolabile ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85.
Mayer A, Gropper R, Schwartz AL, Ciechanover A. Mayer A, et al. Among authors: ciechanover a. J Biol Chem. 1989 Feb 5;264(4):2060-8. J Biol Chem. 1989. PMID: 2914892
Therefore, mutant cell lines with conditionally altered function(s) of the ubiquitin system can serve as powerful tools in studying the degradation of stable cellular proteins. We have characterized a temperature sensitive cell cycle arrest mutant cell (ts85) with a
Therefore, mutant cell lines with conditionally altered function(s) of the ubiquitin system can serve as powerful tools in studying the degr …
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